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別墅

積分: 973


發表於 20-9-4 18:12 |顯示全部帖子
Hi Cutecutetown

之前有同你提過我嘅基礎體溫比一般低0.5度,網上見到好多fertility dietians話同thyroid健康好大關係。請問我需要做DUTCH test 嗎?謝謝!


大宅

積分: 2015

2020勳章


發表於 20-9-6 05:32 |顯示全部帖子

回覆樓主:

Hi Cutecutetown,

早幾天做了第2次ivf抽卵,抽了22個卵子,有12個受精,準備去培養囊胚,暫時未知有多少,但醫生抽血後建議我下星期嘗試植入1個鮮囊胚,其他囊胚做雪胎,我記得最後抽卵前陰超,內膜厚度已經有17mm, 會否過厚不適合?

去年做了1次ivf, 有6個雪胎囊胎,1次化學,1次溶解時爆裂,4次完全冇著床。

所以今次都想上下植入鮮胎,有朋友說可嘗試食亞士匹靈,以助著床,其實我沒有任何免疫/凝血問題,可服用輕劑量嗎?

謝謝解答


男爵府

積分: 7564


發表於 20-9-6 15:52 |顯示全部帖子
Shibin 發表於 20-9-4 18:12
Hi Cutecutetown

之前有同你提過我嘅基礎體溫比一般低0.5度,網上見到好多fertility dietians話同thyroid ...

Dear Shibin,
本來度基礎體溫就已經唔係一樣好準嘅嘢。如果你係懷疑自己thyroid有問題,應該係去睇醫生。


男爵府

積分: 7564


發表於 20-9-6 16:03 |顯示全部帖子
sanyosanyo 發表於 20-9-6 05:32
Hi Cutecutetown,

早幾天做了第2次ivf抽卵,抽了22個卵子,有12個受精,準備去培養囊胚,暫時未知有多少, ...

Dear sanyosanyo,
如果內膜過厚,醫生又為乜叫你放鮮胎?
你朋友是醫生嗎?如果要食亞士匹靈,知道要食多少劑量,何謂輕、何謂重?
其實如果要食,跟自己醫生說說是很簡單的事,最忌是你以為很簡單而不跟主診醫生說,你知道要什麼時候開始服、幾時要停服嗎?


別墅

積分: 973


發表於 20-9-7 07:04 |顯示全部帖子
cutecutetown 發表於 20-9-6 15:52
Dear Shibin,
本來度基礎體溫就已經唔係一樣好準嘅嘢。如果你係懷疑自己thyroid有問題,應該係去睇醫生。
...

好的,我下次見醫生時提出。謝謝。


大宅

積分: 2015

2020勳章


發表於 20-9-11 13:09 |顯示全部帖子
cutecutetown 發表於 20-9-6 16:03
Dear sanyosanyo,
如果內膜過厚,醫生又為乜叫你放鮮胎?
你朋友是醫生嗎?如果要食亞士匹靈,知道要食多 ...

謝謝你的意見


民房

積分: 27


發表於 20-9-12 15:02 |顯示全部帖子
cutecutetown 發表於 20-8-22 13:27
Hello LamLam1234_FB,
如果仍然不想做ivf(各種原因也有,例如想「自然一點」懷孕、信仰、夫婦其中一方抗拒 ...


Cutecutetown你好、
之前問了一些意見...
有些奇怪事情希望你抽空解答...
之前我c6 8月驗精(家計會做)發現密度、向前活力及形態分別有10, 14% and 10%

我比左d supplement Menevit 食用及叫c6多跑步。佢好聽話有做到。

今個9月佢去仁安做多次,
結果係密度、向前活力及形態分別 75、48%...但形態係<1%....

醫生話家好小見到形態有10%、覺得家計會亂來...

為何分別這麼大...是否menevit影響...

這一個月c6生活環境沒有太大轉變的...亦冇食煙飲酒...


男爵府

積分: 7564


發表於 20-9-15 13:09 |顯示全部帖子
LamLam1234_FB 發表於 20-9-12 15:02
Cutecutetown你好、
之前問了一些意見...
有些奇怪事情希望你抽空解答...

Dear LamLam1234_FB,
我之前亦有回覆過。
在驗精報告的三項重要指數中(密度、活動力、型態),型態是最為主觀的,亦即是說,這一項在不同技術員、不同地方化驗時的出入最大。純粹基於我看過仁安的驗精報告,沒幾個人的精子型態是高過1%的!你相信也好,不信也罷,我只能勸說你真的不要太在意型態,尤其當精子密度/數量和活動力是正常時,想先試iui是無妨的。


民房

積分: 14


發表於 20-9-22 23:04 |顯示全部帖子
Hi cutecutetown,

I am 34 with normal AMH level, my husband’s sperm morphology is 1% and we have been trying to conceive for 2 years and done IUI twice but unsuccessful. I finally did ivf in Jul and retrieved 28 eggs with 19 fertilized, ended up with 4 frozen embryos: 1 day 3 grade B embryo, 1 day 5 grade B 4cc embryo and 2 day 5 grade B- 4cc embryos. I transferred the day 5 grade B 4cc embryo and ended up with heavy bleeding when I was at 5.5 weeks. My doctor said the quality of my embryos are only so-so and suggest I can go for another egg retrieval and this time with the adjustment of hormone injections to enhance the egg quality and less quantity. Also, doctor suggested to go for a hysteroscopic examination and curettage prior to my next embryo transfer which will perhaps increase the chances of implantation.

I would like to seek your advise to see if the quality of my embryos are really that bad and should I go for another egg retrieval instead of giving another chance to transfer my existing frozen embryos that are only grade B- 4cc.

Also, do you think a hysteroscopic examination and curettage would help?

Many thanks for your help in advance and look forward to hearing from you.


男爵府

積分: 7564


發表於 20-9-23 16:13 |顯示全部帖子
Littlewing123 發表於 20-9-22 23:04
Hi cutecutetown,

I am 34 with normal AMH level, my husband’s sperm morphology is 1% and we have be ...

Hello Littlewing123,
You mentioned you had a day3 grade B embryo; have you transferred it yet? Do you know what cell stage was it, 8-cell, 6-cell, or what?
Keeping in mind that embryo grading is not very objective, I am not familiar with your day-5 grading where the embryo is grade B but also 4cc. My opinion is that your day3 embryo may still have a chance (if we know its cell stage), while the two 4cc probably have poor chance of success.
Hysteroscopic examination should help to find out if there is anything unusual inside the uterus. This does no harm if no benefit when your uterine cavity is normal. However, by curettage I hope you are just using the wrong word; my guess is endometrial scratching.


民房

積分: 14


發表於 20-9-23 22:55 |顯示全部帖子
回覆 cutecutetown 的帖子

Hi cutecutetown,
Thank you for your prompt response, much appreciated!

It does sound like the quality of my frozen embryos are quite poor. Do you think it is worth doing another egg retrieval process since my doctor said she will adjust the injection dosage to help improve the egg quality if I go for a next trial or should I risk to transfer the 2 4cc embryos that I have?

Regarding curettage, this is the exact wording that was provided by my doctor but I think it is the idea of endometrial scratching, do you think it does help for future implantation? I just don’t know if I should be undergoing a minor surgery if not necessary.

Thank you!


別墅

積分: 973


發表於 20-9-24 18:18 |顯示全部帖子
Hi Cutecutetown

我尋日抽左12粒卵子,有6粒成功受精。醫生話會day 3植入。想了解一下day 3植入同day 5植入有咩分別?

我之前提過我超高齡,又見到forum上好多準媽媽都做PGS先植入,請問我應該向醫生提出做PGS嘅要求嗎?

另外,我有咩要注意或者可以做啲咩提高著床成功率?

謝謝!


男爵府

積分: 7564


發表於 20-9-25 00:24 |顯示全部帖子
回覆 Littlewing123 的帖子

Dear Littlewing123,
I don't see why you cannot transfer the day-3 embryo. It is my guess that when your 19 fertilized eggs were being cultured, only one grade B embryo was available on day-3, while the other embryos all appeared to be poor. That's why one embryo was frozen on day-3. The remaining poor-quality embryos continued culture until day 5, on which day there were 3 blastocysts, one grade B, two grade B-.

I will definitely try the day-3 embryo first before considering another egg retrieval.

If curettage is the exact word, I am very skeptical if it will help at all. I cannot even see any reason for a curettage. Suppose she said the wrong word and actually really meant endometrial scratching, I doubt if it will help in your case. Endometrial scratching is believed to work when embryos do not implant; in your case, your embryo implanted but miscarried.

Good luck,
cutecutetown


男爵府

積分: 7564


發表於 20-9-25 13:02 |顯示全部帖子
Shibin 發表於 20-9-24 18:18
Hi Cutecutetown

我尋日抽左12粒卵子,有6粒成功受精。醫生話會day 3植入。想了解一下day 3植入同day 5植 ...

Dear Shibin,
印象中你上次ivf的胚胎質素不太好,所以醫生才建議放day3, 因為再培養多兩天到day5的話,胚胎可能不能生長到囊胚,那就沒有胚胎可放。
如果day3胚胎已經質素差,一般都很難生長成囊胚,原因大多數也是胚胎在每一次細胞分裂時,染色體數目的分配出錯,若此時有做PGS都可以分析得到。
做PGS的大前題是胚胎要是囊胚,因這階段已有了幾天的篩選,淘汰了一些如上所說不正常或不會生長的。但如果培養到第五或六天,只有一個囊胚,又是否值得做pgs呢?尤其放胚胎在很多jm眼中也是一個大里程碑時,如果沒其他特別原因(例如慣性流產),其實我都會建議放胎。


別墅

積分: 973


發表於 20-9-25 15:07 |顯示全部帖子
回覆 cutecutetown 的帖子

謝謝你,Cutecutetown


別墅

積分: 973


發表於 20-10-9 17:17 |顯示全部帖子
Shibin 發表於 20-9-25 15:07
回覆 cutecutetown 的帖子

謝謝你,Cutecutetown

hi Cutecutetown

我第一次放胎,一個Day 3 Grade 1同一個Day 3 Grade2嘅鮮胎,兩個都未能成功著床。我仲有四個雪胎,請問我下一步應該點好?點樣可以提高著床機會?謝謝。


男爵府

積分: 7564


發表於 20-10-11 13:05 |顯示全部帖子
Shibin 發表於 20-10-9 17:17
hi Cutecutetown

我第一次放胎,一個Day 3 Grade 1同一個Day 3 Grade2嘅鮮胎,兩個都未能成功著床。我仲 ...

Dear Shibin,
如我在post #5234所說,卵子本身是年紀越大,質素越差;就算是受精了,胚胎在成長時每一次做細胞分裂,都有機會出現問題,有時細胞可以自我修復、有時不可以。年紀越大,細胞越大機會出錯,修復能力也可能隨年齡下降。
你今次一次ivf就有6個day3胚胎嗎?有6個胚胎可以雪,其實在你的年齡層已是很好了(我翻看了你第一個post). 就是因為上述因素,6個胚胎之中,不會全都能成功的,會成功的可能只有兩個、一個、又或冇?所以只能繼續放胎,胚胎基本上已定局了,沒有什麼可以改變他們本來的質素。


別墅

積分: 973


發表於 20-10-11 23:00 |顯示全部帖子

明白,謝謝你cutecutetown。希望日後會有好消息同大家公佈。


複式洋房

積分: 204

2020勳章


發表於 20-10-15 14:50 |顯示全部帖子
cutecutetown 發表於 10-2-12 11:02
Being in the ivf field for >10 years, I hope to help in a discussion format any of your questions or ...

Hi Cutecutetown,

I am 40 years old , I have three Day 5 AA grade embryo ,do you think I need to do the PGS?
I am afraid of the chromosomal abnormalities.

What’s the successful rate of embryo implantation?

Look forward to hearing from you soon


男爵府

積分: 7564


發表於 20-10-16 15:42 |顯示全部帖子
Sunshinehehe 發表於 20-10-15 14:50
Hi Cutecutetown,

I am 40 years old , I have three Day 5 AA grade embryo ,do you think I need to do ...

Dear Sunshinehehe,
Have you ever transferred any embryo in the past? Any pregnancy before, natural or ivf?
Since you have already frozen these 3 embryos, you will need to thaw and re-freeze if you want PGS to be done. I will suggest to try once transferring 1 or 2 embryos without PGS. See what the outcome is and decide later if you want the remaining embryo(s) to do PGS.
Very general statistics tells us that there’s perhaps a 10-15% chance of implantation in your age range. Implantation is not equal to live birth though. PGS may bring implantation up to ~60%, but that’s when you have a euploid embryo. You will need to balance the risk of aneuploidy (chromosomal abnormalities) and having no embryo for transfer.

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