You are right, the chance of abnormality like last time should be very low. Besides, unless both embryos are equally competent, there may be chances where only 1 implant, or no implan ...
When embryos of good quality are frozen, and then thawed later, they will revive and show signs of growth (e.g. 再分裂). This is usually the case, given the embryos have good potential and the freeze-and-thaw process has not caused any damage.
If, let's say, the embryos cannot survive freezing and/or thawing, they may degenerate immediately after thawing. Sometimes, when we give time (usually by overnight culture) to embryos of poorer quality, they may still degenerate the next day, or simply not continue to divide.
To put in simpler terms, suppose an embryo has the potential to become a baby, it will do it whether it is transferred fresh or frozen; but if an embryo does not have that potential, it will not do any good even when transferred fresh.
So, although we like to see and compare success rates, we have to also bear in mind that there is a chance of failure as well. We wish every couple can walk out with a healthy baby, but at the same time, for those who can't, we don't want them to walk out depressed and traumatized.
Given your history and the past few years of taking care of your current child, it may be quite stressful to put yourself back into an FET preparation. Take it easy and we are all here to walk through the path with you.
It's rather difficult for me to recommend any doctor due to conflict of interest. I can only tell you that because of your age, you can't do the public line anymore; seeking a private doctor is your only choice.
See if some jm here can give you some recommendations. Look around in other postings too, some of them are quite clear by the way they named the blogs.
Good luck, cutecutetown
原帖由 jojoalison 於 10-5-14 16:15 發表
Hi cutecute town,
Can you help me? i have no idea for this. any O&G doctor recommend to me? Many tks!
Would like to let you know my doctor changed me to orgalutran cycle for my 2nd ivf ... hope it helps to grow more follicles la! Now just waiting my next period to come~
I have a question here ... I'm considering to transfer 2 embyros (if available) ... but what I'm worrying about is ... if both of them can implant ... but one of them miscarry later (touch wood) ... will it affect the healthy one? i.e. will the healthy baby miscarry/hurt by the miscarriage of the other one?
This is more of a medical question; I suppose it really depends on when along the pregnancy when it happens, if it should happen at all. My limited experience is that when it is early in the pregnancy (some time before 12 weeks of gestation/1st trimester), it doesn't seem to affect the living fetus. It may also depend on how far each implantation site is away from each other.
Definitely ask your doc about the chances and pros & cons of transferring 2 embryos. The decisions will depend on a combination of your acceptance of twin pregnancy, your age, no. of ivf you previously had, and also the embryo quality. Don't get over-worried at this point yet, your doc will probably give you recommendations too.
Good luck and "happy period" :)
cutecutetown
原帖由 rubyhomffc 於 10-5-16 07:32 發表
Hi Cutecutetown,
Good morning~
Would like to let you know my doctor changed me to orgalutran cycle for my 2nd ivf ... hope it helps to grow more follicles la! Now just waiting my next period to come ...
Hello cutecutetown, first of all thank you so much for sparing your time to answer our questions. You know how helpless sometimes during the ivf journey.
My case - I have two miscarrage consecutively one in Apr 2009 and Feb 2010 - both were at the time the embyro was 8 weeks (not sure if it stopped growing at 8 weeks but so happened I did my regular check at around that time).
My question - is IVF something I can try to increase the live-birth rate? I am thinking it will because 1) doctor will pick the good looking ones, and assume good-looking ones have higher chance of being a normal ones; 2) I have at least 2 chance each transfer, doctor usually transfer more than one; 3) I am under close monitoring and medication to support after transfer.
I forgot to mention my age. I am 38, and turning 39 in a few months time.
原帖由 lee028 於 10-5-17 00:06 發表
Hello cutecutetown, first of all thank you so much for sparing your time to answer our questions. You know how helpless sometimes during the ivf journey.
My case - I have two miscarrage consecutive ...
I might have misunderstood you, were your last 2 miscarried pregnancies from natural conception or from ivf?
Let's not biased by your miscarriage yet because natural conception and ivf are quite different in management but similar in other ways. To answer your questions from an ivf perspective,
1. Yes, good-looking embryos have a better chance of being normal, very generally speaking;
2. Based on your age, your doc will probably recommend to transfer two embryos. However, the chance for multiple pregnancy will increase, the risks associated will be fully explained by your doc;
3. the monitoring will be done as appropriate, it may be more frequent than a natural conception, but yet it won't be an everyday check. Medication after transfer (of fresh embryos) is necessary because ivf is an "artificial" cycle simulating a natural one. In natural conception, or frozen embryo cycle where the natural ovulatory cycle is utilized, no medication is required.
I think your doc (the one dignosing and taking care of the miscarriages) may give you better advice if you have not done an ivf before.
Hope the info here so far is helpful.
cutecutetown
原帖由 lee028 於 10-5-17 00:06 發表
Hello cutecutetown, first of all thank you so much for sparing your time to answer our questions. You know how helpless sometimes during the ivf journey.
My case - I have two miscarrage consecutive ...
Hi cutecutetown,
Thanks for your response. The two miscarried pregnancies were from natural conception. And I really worry to conceive naturally again as I worry it will turn out to be another failure. I did ask my gyn - but he didn't give me a very solid recommendation. From your opinion, do you think ivf can give me a better chance of carrying the baby to full term?
原帖由 cutecutetown 於 10-5-17 15:04 發表
Hello lee028,
I might have misunderstood you, were your last 2 miscarried pregnancies from natural conception or from ivf?
Let's not biased by your miscarriage yet because natural conception and ivf ...
As previous stated, I am going to FET next cycle, but now am very concern my high hormone rate which is 3,000 before receiving any injections. I am not sure if this high hormone caused by eating " 花膠", anyway I stop to eat it now. Can you please advise the standard of hormone which accepted to proceed 放胎? By the way, do you know how to lower the hormone by eating or not eating somthing through your sophisticated experience of dealing infertility cases? sorry now that I treat you like a doctor but you are the one I can count on cause I couldn't get to see my doctor until 放胎 . Thank you.
By definition, we (the ivf bunch) consider the condition of recurrent miscarriages as those who miscarried 3 times or more. However, I do see you are heart-broken with the last 2 losses and also you are getting older. My suggestion is perhaps to get an initial consultation with an ivf doctor/specialist and decide from there if you are really suitable for and accepting the treatment. Given you don't seem to have trouble conceiving, there may be easier alternatives.
Good luck and update us your progress. Best wishes from cutecutetown
原帖由 lee028 於 10-5-17 23:08 發表
Hi cutecutetown,
Thanks for your response. The two miscarried pregnancies were from natural conception. And I really worry to conceive naturally again as I worry it will turn out to be another failu ...
Oops, I still haven't given you anything solid, have I?!
The chance of carrying a baby to term can't be an easy promise. However, looking from the other end of the perspective and also basing on experience from ivf, these miscarried fetuses often have some kind of genetic abnormality, such as aneuploidy (abnormal number of chromosomes). If the parents have known family history of genetic disorders, aborted fetuses may have also carried the problem. Another less-likely possibility is some underlying uterine factor, e.g. fibroid. That's why you may want to consult an ivf specialist, at least to rule out some of these factors so that you will be confident again with future natural conception.
cutecutetown
原帖由 lee028 於 10-5-17 23:08 發表
Hi cutecutetown,
Thanks for your response. The two miscarried pregnancies were from natural conception. And I really worry to conceive naturally again as I worry it will turn out to be another failu ...
I am assuming your natural ovulatory cycle is normal and therefore, your doc will simply monitor your natural cycle for the FET. No medication is required in most women. If this is the case, you don't have to worry about any high or low hormone.
Utilizing your own natural cycle, we are simply putting the embryo(s) back at the right time so that the uterus is in synchrony with the implanting embryo. This is almost like a natural process of pregnancy, except the embryo(s) were from a previous ivf cycle. As far as hormone levels go, they should all be within biological range.
Food and/or supplements, my recommendation is to eat normally and maintain a balanced diet; in other words, do not over-eat such as in a buffet. Try to stay away from raw food and greasy food so that you don't get a diarrhea, food-poisoning, or bacterial infection. If you get nervous or emotional for any reason or no reason, try a piece (or a few pieces) of chocolate :)
Cutecutetown
原帖由 susan19771118 於 10-5-18 10:09 發表
Hi Cutecutetown,
Hope you are going well.
As previous stated, I am going to FET next cycle, but now am very concern my high hormone rate which is 3,000 before receiving any injections. I am not sure ...
Sorry that I have got quite a number of questions regarding ivf since I have just started my way with the other jms here.
My case: had done 4 times iui before, and all were failed, thought that it was because I had 2 operations of remving chocolate cysts before. I am now 36 years old.
This cycle, I turned to ivf in May, and started to inject 450iu gonals from day 2 - day 6; and 150 iu (the one cheaper than gonals) with 300iu gonals on day 7- 8. After that , those 6 eggs have not grown as expected. The opinion from my dr is that my response to pill was much stronger than injection, tracing by iui history. Therefore, I have to go back to iui this time and will see my dr again on 19/5. She said that in case I have the other ivf next time, I better take pill first following with injection.
How come I have to face this "accident"? I was so disappointed. Much more money for the iui this time then. Have you heard similar case before? Loooking forward to receiving your advice.
Thanks for your explanations and suggestions to my diet. I'm clear with all of that except this sentence "except the embryo(s) were from a previous ivf cycle." Can you please advise what is the difference of putting embryo (s) in to uterus from this IVF cycle and from previous IVF cycle? Thanks again.
Susan
原帖由 cutecutetown 於 10-5-18 12:01 發表
Dear Susan,
I am assuming your natural ovulatory cycle is normal and therefore, your doc will simply monitor your natural cycle for the FET. No medication is required in most women. If this is the ...
It's sad, but sometimes it happens. To give you a rough estimate, my center has about 5% of "planned ivf" cases being converted to iui every month. And do not give up yet, I have also seen these ivf>iui cases getting pregnant; although the chance is somewhat low, nothing is absolute.
I am not certain what you meant by "those 6 eggs have not grown as expected"; I assume you probably had 6 follicles that grew too slowly. If so, it will be even more costly to invest further time, efforts, and money to keep them growing because drugs, surgery fee, lab fee, emotional stress all add up to a probable poor outcome. To keep you on the bright side, your dr now knows your responses better and he/she will certainly make your next ivf cycle work.
Good luck on your dr visit tomorrow.
cutecutetown
原帖由 ada1103 於 10-5-18 12:15 發表
Dear cuecuetown,
Sorry that I have got quite a number of questions regarding ivf since I have just started my way with the other jms here.
My case: had done 4 times iui before, and all were failed, ...
Sorry I confused you. What I meant was that you are now preparing for a Frozen Embryo Transfer (FET). The frozen embryos were from your ivf cycle last time (~1 month ago?); in other words, these embryos were derived from that fresh ivf treatment.
The main difference between a fresh embryo transfer and a frozen embryo transfer is that in a fresh one, your body has just been subjected to a lot of exogenous hormones (hormones from an outside source). The purpose of the ivf stimulation is to 'override' your natural ovulation cycle so that more than one mature egg can be produced. And because of this 'override', the uterus needs support medication after ET. On the other hand, in a frozen embryo transfer, we do not give you exogenous hormones to produce eggs and in most cases, we do not give support medication after FET. Instead, we simply utilize your natural ovulation cycle so that if the embryo implants, the pregnancy event will take over and no period returns; in other words, if the embryo fails to implant, the menstruation begins according to its natural timing.
I hope I haven't confused you further...
cutecutetown
原帖由 susan19771118 於 10-5-18 12:25 發表
Hi Cutecutetown,
Thanks for your explanations and suggestions to my diet. I'm clear with all of that except this sentence "except the embryo(s) were from a previous ivf cycle." Can you please advise ...