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282^#

發表於 10-5-28 11:15 |只看該作者

Hello newcomer8,

First of all, if your wife is 40 years old or above, then I don't think she will be accepted into the public queue. You will need to enroll as a private case, the line of which should be much shorter but the cost will be higher.

Other than the semen analysis, has your wife gone through any fertility assessment yet? Although your sperm morphology was 4% with other parameters normal, and assuming she has no infertility issues such as blocked tubes, endometriosis, etc, I am afraid that the iui success rate may still be very low. Please consider ivf, but be prepared that it will cost more time and money. See a ivf specialist and he/she will give a more detailed assessment for you.

cutecutetown

原帖由 newcomer8 於 10-5-28 10:40 發表
Dear Cutecutetown,

I got my sperm report in 東區醫院 few days ago, the report stated that density and motility is normal but the morphology is only 4% (normal is 15%), the doctor advised me to do ivf ...

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novelle

別墅

積分: 930

283^#

發表於 10-5-28 16:34 |只看該作者

Thanks for your detailed explanation cutecutetown! You mentioned past history of miscarriage, as I've miscarriage before, is the possibility of next miscarriage is higher? Thank you.

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284^#

發表於 10-5-29 21:11 |只看該作者

Dear novelle,
If not counting the recent miscarriage, did you have 1 miscarriage in the past, or more? If you plan to proceed with another ivf cycle, talk to your doc and see if there is anything he/she can offer to minimize such an event.
Best wishes, cutecutetown

原帖由 novelle 於 10-5-28 16:34 發表
Thanks for your detailed explanation cutecutetown! You mentioned past history of miscarriage, as I've miscarriage before, is the possibility of next miscarriage is higher? Thank you.

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juniejunie

複式洋房

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285^#

發表於 10-5-30 23:50 |只看該作者

Dear Cutecutetown,

I have PCOS and one blocked fallopian tube. I started my first ivf in apr and had serious OHSS after egg retrival on 21 apr (51 eggs retrieved on that day). I was hospitalised for 7 days and dischagred with 1 month anti-coagulant drug as the internal medicine specialist suspected some capillaries blockage.

My Gyn said I finally have 17 embroys (11 G1/G1-, 6 G2), where 3 of them were 8-cells. Since I hve OHSS, my gyn freezed all my embryos and rest during May. She said I should be able to have FET in the coming cycle.

Here are my questions:
1. Will I have OHSS again after FET? I am so scared that it will affect my chance of bingo.....although I said my blog that having OHSS after ET/FET is a good sign.

2. Since I have some 8-cells embryos, my gyn said I can choose to transfer just one or two if I am prepared to have twins. Is it true that the more cells the embryos have, the easier they wil implant and grow all the way to be born?

3. I saw some journals that PCOS suffers is proned to miscarriage, if so, is it due to the quality of eggs? Would bed resting help to stablise/retain the embryos after successful implant?

4. What are the risk of PCOS suffers if they carry twins?

Sorry for so many questions, I feel so relieved after discovering your post. I really hope you can give me some advice as I should be able to have FET towards the end of June.

Thanks a million!!

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286^#

發表於 10-5-31 10:30 |只看該作者

Hello juniejunie,

That's a lot of eggs you've got!! I hope you do feel better and have physically recovered. Women who have PCOS also have a higher chance of developing OHSS; and in your case, it looked like a very severe one.

1. If your natural cycle is utilized for FET, you will not have OHSS. Only when ovarian stimulation drugs (FSH and/or HMG) are used, then there will be a risk.
**OHSS is NOT a good sign. Well, women who ended up having OHSS looked like they bingo easier. This is rather deceiving; in fact, due to the pregnancy/implanted embryo, the hCG level rises, further increasing the chance and severity of OHSS. A mild OHSS is usually medically manageable, however, a severe one is life-threatening. I think the health of the mother is the most important.

2. Very generally speaking and on relative terms, yes, the more cells the embryos have, the higher chance they will implant. It is very difficult to say if the implanted embryo will grow all the way to term though. Suppose there is no known or identifable factor affecting a pregnancy, the chance of a miscarriage is still very similar whether the pregnancy is from IVF or natural conception.

3. Not sure, bed resting may help (but not a lot); you can seek advice from your doc because he/she knows your physical conditions well.

4. A woman's age, embryo quality, number of embryo(s) transferred, and her previous infertility history affect the chance of a twin pregnancy. PCOS alone will not increase the risk.

I suppose you are relatively young (age<35) and this is your 1st-time ivf. If you do worry about getting twins (e.g. physically you are at a higher risk, the fetuses may have a higher chance of pre-term delivery, and also costs after birth), you should opt for 1 embryo, especially if it is of good quality.

Alternatively, have the lab thaw out 2 embryos. In most labs including mine, we thaw embryo(s) the night before to give them time to revive. On the morning before transfer, see if both embryos are good and only then, decide with your doc how many you want to transfer. Any good-quality embryo can be re-frozen if it is required.

All the best,
cutecutetown

原帖由 juniejunie 於 10-5-30 23:50 發表
Dear Cutecutetown,

I have PCOS and one blocked fallopian tube. I started my first ivf in apr and had serious OHSS after egg retrival on 21 apr (51 eggs retrieved on that day). I was hospitalised fo ...

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wendycyp

積分: 1882

好媽媽勳章

287^#

發表於 10-5-31 17:24 |只看該作者

Hi cutecutetown,

我最終28/5無做到FET, 因為醫生話兩個frozen embryos溶咗之後爛爛地, 唔適合做, 就算放咗胎都唔會成功喎, 所以叫我唔好試.

雖然我同老公都唔係太明白佢所指爛爛地係咩意思, 不過既然佢話唔適合做, 我都唔會勉強, 如果做咗之後唔成功, 又會令自己更加失望!

Anyway, 我同老公都會順其自然, 並且好好照顧而家呢個小朋友! 好多謝你一直用心解答同支持, thanks a lot and wish you all the best!

亦希望其他努力緊嘅jm可以成功, good luck!

原帖由 cutecutetown 於 10-5-14 17:45 發表
Dear wendycyp,

When embryos of good quality are frozen, and then thawed later, they will revive and show signs of growth (e.g. 再分裂). This is usually the case, given the embryos have good potentia ...

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積分: 9486

288^#

發表於 10-6-1 09:21 |只看該作者

Dear wendycyp,

Thanks for your sharing. Your doctor was probably right; I am glad that you hold a very positive attitude.

Enjoy your family life with this little one. Time passes by and you will soon think she's growing up too quickly

Best wishes, cutecutetown

原帖由 wendycyp 於 10-5-31 17:24 發表
Hi cutecutetown,

我最終28/5無做到FET, 因為醫生話兩個frozen embryos溶咗之後爛爛地, 唔適合做, 就算放咗胎都唔會成功喎, 所以叫我唔好試.

雖然我同老公都唔係太明白佢所指爛爛地係咩意思, 不過既然佢話唔適合做 ...

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novelle

別墅

積分: 930

289^#

發表於 10-6-1 19:15 |只看該作者

hi cutecutetown,
I bingo twice from ivf but both miscarriage, is doctor has any ways to minimize this? My doc just said the embroy is not good. Thanks

原帖由 cutecutetown 於 10-5-29 21:11 發表
Dear novelle,
If not counting the recent miscarriage, did you have 1 miscarriage in the past, or more? If you plan to proceed with another ivf cycle, talk to your doc and see if there is anything he/ ...

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積分: 9486

290^#

發表於 10-6-2 09:27 |只看該作者

Dear novelle,

As mentioned in earlier & other postings, usually it's the embryo that is not good. A good grade at early development sometimes does not translate to a good fetus of few months later.

Early miscarriage is often due to chance, however, it is still devastating enough especially for our group here. About 2 weeks ago there was also another jm having miscarriage issue with her natural bingo and she chose to do ivf. I need to emphasize again in this posting that generally speaking, miscarriage rate of ivf is similar to miscarriage rate of natural pregnancy.

I did also suggest PGD in the past which theoretically may help; however, I retain my skepticism with the current methodology. The next alternative will be to culture your embryos to day 5 to select the more competent embryos. On a conservative management, we won't recommend you to do so if you only have very few embryos (e.g. less than 6 embryos on day 3). You may scroll back a little to check the earlier posts.

To look from the bright side, you seem to have no trouble getting pregnant. Very likely that you have a receptive uterus but not a "well-behaved" embryo. Wish you the best of luck in your forthcoming cycle.

cutecutetown

原帖由 novelle 於 10-6-1 19:15 發表
hi cutecutetown,
I bingo twice from ivf but both miscarriage, is doctor has any ways to minimize this? My doc just said the embroy is not good. Thanks

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pibb

積分: 6810

291^#

發表於 10-6-2 16:57 |只看該作者

Dear cutecutetown,
I got a question about crinone and hope you can help to answer it. Should i stay still or take a slow walk after using it? The nurse suggested that mild activities help my body to absorb the gel. But on the other hand, i heard many people saying that we should stay still for at least 15 mins. I'm confused..

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積分: 9486

292^#

發表於 10-6-3 09:08 |只看該作者

Dear pibb,
Listen to the nurse. Crinone is a progesterone (medication) in gel form. Mild activity may help absorption, you do not have to stay still.
cutecutetown

原帖由 pibb 於 10-6-2 16:57 發表
Dear cutecutetown,
I got a question about crinone and hope you can help to answer it. Should i stay still or take a slow walk after using it? The nurse suggested that mild activities help my body to a ...

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幸福大少奶

積分: 1030

293^#

發表於 10-6-3 12:56 |只看該作者

Cutecutetown,

Today I just confirmed the failure of my 1st ivf treatment.

My case is "unexplained infertility". I had tried 2 times IUI last year but also failed. My FSH is 5 (same as last year). I injected 112.5iu for 5 days could get 4~5 follicles in 2 IUIs. However, this year I injected 225iu for 5 days could only get 6 follicles (actually 4 follicles were in good sizes). We insisted to continue ivf treatment. Finally 5 eggs were retrieved and 4 eggs could be fertilized. Finally 3 embryos (2 grade 1- & 1 grade 2) were transferred on Day 14. My Dr said my success rate was 50% but failed…

I really don’t know I got only a few eggs and my failure was caused by the emotional factor. My working pressure was suddenly very high during the treatment. On Day 5 after ET, my close family member suddenly died and I cried > 10times in a few days. Perhaps Day 5~7 is really critical for implantation. I really tried my best to go through every step in the treatment.

Do you think I should take a rest at least 2 cycles if I want to try ivf again? Is there any “accumulated success rate” for ivf? I will consult QM Dr in the public queue this year end. I don’t know if I should take more rest in the meantime or continue to try the 2nd ivf a few months later. Please advise.

Many thanks!
God bless!

[ 本帖最後由幸福大少奶於 10-6-3 16:02 編輯 ]

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novelle

別墅

積分: 930

294^#

發表於 10-6-3 13:08 |只看該作者

Dear Cutecutetown, thanks for your professional advice and comfort. I will try the next ivf again, hope can suceed.

原帖由 cutecutetown 於 10-6-2 09:27 發表
Dear novelle,

As mentioned in earlier & other postings, usually it's the embryo that is not good. A good grade at early development sometimes does not translate to a good fetus of few months later.
...

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積分: 9486

295^#

發表於 10-6-3 18:05 |只看該作者

Dear 幸福大少奶,

My codolences to your recent loss of a close family member. I feel so sorry for you having to go through several stressful events within such a short time. It's not easy to recover; don't push yourself too hard. You are allowed some time to re-gain the strength for your mind and your body before anything else.

Don't judge your response simply based on the dosage. When the doc plans an iui cycle, he/she will use a much lower dose as compared to an ivf. Although the egg number was not plentiful, they were fertilized fine, also giving good-quality embryos. I would call this cycle a reasonable one.

I agree that you should take a rest; let's say after 2 months, ask yourself this, "Am I ready for my 2nd ivf?" If not, do not force yourself (and also your husband). Your public queue is coming soon, so if you really can't, rest a little more and you will be ready for the cycle year end.

To answer your question regarding "cumulative success rate", yes, but it is not a simple math. of addition. We often look at the first 3 ivf/et cycles only; beyond 3 cycles are more complicated. There is not a numeric figure I can tell you because it varies with age and infertility causes. But the general trend is that it rises at first, then slow down and eventually plateau. In other words, it cannot reach 100% success rate (this is a graph drawn from averaging the data).

Hope I have helped. Be faithful, have trust in Him. Follow Him, and then listen to what your heart really tells you.

cutecutetown

原帖由 幸福大少奶 於 10-6-3 12:56 發表
Cutecutetown,

Today I just confirmed the failure of my 1st ivf treatment.

My case is "unexplained infertility". I had tried 2 times IUI last year but also failed. My FSH is 5 (same as last year). I ...

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幸福大少奶

積分: 1030

296^#

發表於 10-6-3 23:03 |只看該作者

cutecutetown,

Thanks for your reply & support. I will take a rest for a few months & enjoy life more before trying the 2nd ivf.

That's life. We cannot take the control. I believe God has prepared the best for me already. It's just a matter of time.

God bless!

原帖由 cutecutetown 於 10-6-3 18:05 發表
Dear 幸福大少奶,

My codolences to your recent loss of a close family member. I feel so sorry for you having to go through several stressful events within such a short time. It's not easy to recover ...

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BiBi100

積分: 2941

297^#

發表於 10-6-3 23:11 |只看該作者

Dear Cutecutetown,

I am going to do my 4 IVF tmr, my first IVF was success and my bab was 2 8 months now. But I want to have one more, so I did IVF again on May 2009 and Dec 2009, but failed. Both the treatment, I do not have very good respond, they normally have 5 - 7 eggs and they are not in high grading too after ICSI, as they only grow to 5 cells on day 5. So the doctors told me that this times I start the injection in my natural period cycles, no need to take the nasal spray before the injection, I need to inject another medicine to control the ovulation. The Doc said this treatment may help to increase the no of eggs. Do you know that really can help to increase the no and quality of the eggs? Tks.

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298^#

發表於 10-6-4 09:36 |只看該作者

Hello BiBi100,

Did you mean you will start injection today, or have the egg retrieval today?

The method your doc will/has used is a very common method for women with 'poor' response. It may help, as your doc suggested, to increase the no of eggs; but consider that you had 5-7 eggs in the past, be happy with 5-10 eggs this time. The increase should be in a small magnitude, do not expect a double.

Besides, quality is the key. We (people who work in this area) still have not figured out the 'magic' to improve egg and embryo quality. However, I believe your doc's plan will lead you in the right direction. Good luck with this ivf cycle.

cutecutetown

原帖由 BiBi100 於 10-6-3 23:11 發表
Dear Cutecutetown,

I am going to do my 4 IVF tmr, my first IVF was success and my bab was 2 8 months now. But I want to have one more, so I did IVF again on May 2009 and Dec 2009, but failed. Both t ...

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BiBi100

積分: 2941

299^#

發表於 10-6-4 10:13 |只看該作者

Thanks for your advice. Actually I will see the doc today as this is day 2 of my period , so I think I will start injection.

BTW, have you heard about the "inositol", is it good if take it during IVF treatment? As I found some information from Taiwan about this. Thanks.

原帖由 cutecutetown 於 10-6-4 09:36 發表
Hello BiBi100,

Did you mean you will start injection today, or have the egg retrieval today?

The method your doc will/has used is a very common method for women with 'poor' response. It may help, a ...

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