In the scenario you mentioned:
(a) 29 eggs retrieved >> poor quality embryos
(b) FET with poor quality embryos >> no bingo
In your case:
(a) 26 eggs retrieved >> grade 1 (good quality) embryos;
(b) no FET performed yet.
Don't start creating worries for yourself at this point. We talk about the balance between quantity and quality in very general terms. Other factors such as your age, your reason(s) for ivf, the no. of previous ivf attempts all contribute to this balance.
Please keep in mind that when we read postings of other jm's on BK, they are no doubt very valuable experience being shared. However, do not take things too personally as everyone has a different cause and a slightly different issue. **Know where you are, and be aware of the differences and unknowns.**
cutecutetown
原帖由 susan19771118 於 10-6-11 00:28 發表
Hi Cutecutetown,
I saw there is a sister here mentioned that she failed in several times of FET because of poor quality of embryos which caused by too many (29) eggs retrieved. Please advise if too m ...
Dear Cutecutetown,
I have some more questions. I have checked the size of the eggs yesterday, this is my day 6, Dr found total 9 eggs, sized from 9 – 19, I was told she will retrieve the eggs on Tue, do you know which size is best for retrieving, if the biggest eggs keep growing, it may grow to over 20, do you think it is too old for fertilization?
It's a judgement call by your doctor, based on his/her previous experience with you and/or others. Very generally speaking, we aim at those follicles (containing eggs inside) that are ~18-20mm. The day of stimulation and your hormone levels are also being taken into consideration.
If your retrieval will be on Tue, you will probably need to have the hCG trigger/injection on Sunday night. The length of days you receive injections and your no. of follicles/eggs are about right, compared to average ivf figures. Don't worry about the eggs being over-mature.
Take care & you will do fine.
cutecutetown
原帖由 BiBi100 於 10-6-11 11:24 發表
Dear Cutecutetown,
I have some more questions. I have checked the size of the eggs yesterday, this is my day 6, Dr found total 9 eggs, sized from 9 – 19, I was told she will retrieve the eggs on Tue ...
May I ask what normally would be the body temperature after the transfer of embryo in order to know whether pregnancy is happening or not? My wife is on the third day after ET but record a temperature of about 35.9/36, and she is worried the baby's gone.
Body temperature won't tell if your wife is pregnant or not. It is absolutely NOT the right way to tell if an embryo has implanted; and unfortunately, there is simply no method to know so early if an embryo has implanted. You'll need to wait for ~2 weeks after ET for the first pregnancy test.
In case you/your wife will again look for signs or sharings from other people on BK. Some claim that you will find implantation blood, which again is another misleading fact. In theory, there may be just a small amount of blood around the time of implantation, but this often goes undetectable for many women who later turn up pregnant. Others claim that you may feel nauseated with abdominal pain or cramping soon after ET if you bingo. This is more due to the ovarian/follicle puncture during oocyte retrieval than anything else; although the retrieval needle is very fine, each point of puncture is a wound itself.
So, for these 2 weeks of waiting, try to keep your anxiety level at the lowest because there is simply no way to predict or verify if implantation has occurred. In the meantime, follow your doctor's instruction in taking the luteal support medication. Try to steer your mind away from negative thoughts; watching the Word Cup games may help, or buying your wife some surprise gift(s) if you may
May I ask what normally would be the body temperature after the transfer of embryo in order to know whether pregnancy is happening or not? My wife is on the third day after ET but ...
I have checked the eggs size again today, their size are from 13 - 19, I will inject one more day G-P + Menupur and tmr night will inject medicince for ovulation, Tue will reterive the eggs, hope they will grow more and have suitable and quaility eggs for fertilization.
原帖由 cutecutetown 於 10-6-11 12:09 發表
Dear BiBi100,
It's a judgement call by your doctor, based on his/her previous experience with you and/or others. Very generally speaking, we aim at those follicles (containing eggs inside) that are ...
My 1st IVF was failed last month. I started bleeding since day 6 after ET & it became heavier day by day. My doctor said its not m come and we can do nothing. So, she gave me more medicine and just told me to be patient and wait for the blood test at day 12. The feeling was so bad in this week, my m come on day 11 finally.
This month, i have ET on 5/6. I found small amount of blood last night and this morning(Day8-9). What should I do? am i fail? what's the cause?
How many embryos did you transfer? It looked like you transferred just 1 embryo, which was at 2-cell stage and of grade-2 quality.
A very general guideline: if ET takes place on day2 (count your day of egg retrieval as day0), the embryo should be at 2- to 4-cell stage. Some may see 5-cell or even 6-cell, which should be ok.
If ET takes place on day3, the embryo should be at 6- to 8-cell stage. Again, some may see 10-cell or 12-cell, which is less common but still occurs.
I personally think that grading is very subjective, especially when an embryo contains some degree of fragmentation. You may need to ask your center if you want a very clear-cut definition. Very briefly, a perfect grade (some centers use '1', some use 'A', some use '4', some use '6') means the embryo cleaves nicely with no fragmentation. For grades such as 1-, 2+, B+ usually means the embryo contains less than 10% fragmentation. Grades of 2, B, B- often mean the embryo has 20-30% fragmentation. Grade 3 or C means 30-50% fragmentation. Anything worse I don't think you will get a transfer unless in very special circumstances.
What is fragmentation? In simple terms, it's the remnants or residual cytoplasmic material from cell division. Some of them may be re-absorbed by the embryo in subsequent cell divisions. In humans, fragmentation happens quite frequently and nobody knows if it is an in vitro artifact or not. Do not worry yet, many average-quality embryos give rise to healthy babies.
Call your doctor to see if he/she will give you more medicine. It's still early to give up at this point. Do you get injections, or vaginal support?
Good luck,
cutecutetown
原帖由 allsisi 於 10-6-13 18:01 發表
Dear cutecutetown,
My 1st IVF was failed last month. I started bleeding since day 6 after ET & it became heavier day by day. My doctor said its not m come and we can do nothing. So, she gave me more ...
It’s me again, I have retrieved 12 eggs on 15/06, and it seems quite good. However, after 24 hours, I received the call from my Dr. , she said none of the eggs were fertilized because of the bad quality of sperm. I was very upset. But yesterday morning, I received her call again, one of the eggs was fertilized, 2 cells were found. So I went to the clinic yesterday to do the transfer. At that moment, Dr. showed me the embryo, it found 3 cells, Dr. said it is good, at least it is growing. But when everything is ready for transfer, it change back to 2 cells (1 big and 1 small). So by your experience, have you seen this before, and do you know that this cell is still have chance to grow in my body? Thanks
Was ICSI done on the eggs to begin with? Do you know if all your eggs were mature on the day of retrieval? As your doctor suggested, it's probably the bad quality of sperm because your previous ivf cycles had fine fertilization.
As for the 3-cell>2-cell reversion, I did see it happen before, although not too frequently. We never had enough time to wait for the next cell division before the embryo had to be transferred, but my suspicion is that the cells were still dividing and we were just "lucky" enough to catch that very moment.
Good luck, cutecutetown
原帖由 BiBi100 於 10-6-18 14:52 發表
Dear Cutecutetown,
It’s me again, I have retrieved 12 eggs on 15/06, and it seems quite good. However, after 24 hours, I received the call from my Dr. , she said none of the eggs were fertilized b ...
Thanks for your explainantion. Yes. We did the ICSI, and the eggs were mature enough. And Dr said the sperm sharp were not good, they are all in "Globe" sharp, so she think this is the problem.
原帖由 cutecutetown 於 10-6-21 10:09 發表
Dear BiBi100,
Was ICSI done on the eggs to begin with? Do you know if all your eggs were mature on the day of retrieval? As your doctor suggested, it's probably the bad quality of sperm because you ...
Long time no see! Good to hear that you can finally start the cycle.
When will be your first ultrasound then, day 7/8/9? You probably had a few cycles with similar trends before, so your doctor decided that there will not be much to see even if you have the ultrasound earlier. I think your doctor has seen you today, perhaps also done an ultrasound?! By knowing that you just started your menses and also hopefully with an acceptable E2, there is not much to see until the follicles grow a little more.
Also no worry with the 抑壓針, because this injection will not affect the growth of your eggs. It is prescribed to prevent pre-mature ovulation only.
The blood test on17/6 confirmed FET failed. My doctor advise me to rest for one cycle first. Actually, i don't have any confidence to have ET again although i still have 14 embyros, because the doctor did not mention the reasons of failure.
My doctor said she will use 排卵丸 instead of Estrofem next time. What is the different?
I am sorry to hear the sad news. You will certainly benefit from one cycle of rest first. And if you don't feel up to it, take a total of 2 or 3 cycles. My own experience, as well as some published literature, tells me that when compared with Caucasians, Asian/Chinese women tend to do well in FET but not so much with fresh ET. So, do not get frustrated with your remaining frozen embryos.
Sometimes we just cannot find the exact reason(s) to explain implantation failure. Even when the embryo grading is good, appearance alone can sometimes be deceiving. It's the genetic components of the embryos that often cause trouble.
排卵丸helps with排卵, or time a menstrual cycle so that it occurs in a regular or predictable way with ovulation. Estrofem is mainly estrogen hormone. To my understanding, one of its uses is to improve egg recruitment during the early phase of a cycle.
Do not lose your confidence yet. I believe you are in good hands and your doctor really cares about you.
Best wishes, cutecutetown
原帖由 allsisi 於 10-6-22 01:29 發表
Dear cutecutetown,
The blood test on17/6 confirmed FET failed. My doctor advise me to rest for one cycle first. Actually, i don't have any confidence to have ET again although i still have 14 embyros ...