想生BB 今日: 0 | 主題: 109600

積分: 9498

6201^#

發表於 23-1-17 16:51 |只看該作者

本帖最後由 cutecutetown 於 23-1-18 07:00 編輯

Wisdomjj 發表於 23-1-16 18:06
回覆 cutecutetown 的帖子

Dear cutecutetown Day3 有10個今日day5 得返1個5 bb . 我想請問一下根據你嘅 ...

Dear Wisdomjj,
我自己遇過需要PGT-SR嘅病人似乎都係棘手，就如你一般，幾多day3都好，能去到囊胚的並不多，然後做完PGT後，要balanced或正常的更少。不過就係需要篩走不正常的，否則懷孕了也枉然。
至於點解會咁多都去唔倒囊胚，詳細我好難在此解釋，但與你平衡異位的基因大小和位置也很有關係，因而令卵子和精子結合成胚胎後，胚胎染色體多缺陷，不能正常繼續生長。

私人傳訊回覆引用

Wisdomjj

複式洋房

積分: 465

6202^#

發表於 23-1-18 10:53 |只看該作者

回覆 cutecutetown 的帖子

Dear cutecutetown 明白唯有繼續去試啦希望有小小運多謝你嘅解答

點評

發表於 23-1-22 03:31

私人傳訊回覆引用

積分: 1779

6203^#

發表於 23-1-22 01:57 |只看該作者

樓主你好

想請問 Day 2, 一個6 cell ，一個7 cell , 情況是否很差？

私人傳訊回覆引用

積分: 9498

6204^#

發表於 23-1-22 06:08 |只看該作者

Hapi2017 發表於 23-1-22 01:57
樓主你好

想請問 Day 2, 一個6 cell ，一個7 cell , 情況是否很差？

Hello Hapi2017,
Day2快咗少少，可以睇埋day3甚至day5.

私人傳訊回覆引用

積分: 1779

6205^#

發表於 23-1-22 13:32 |只看該作者

cutecutetown 發表於 23-1-22 06:08
Hello Hapi2017,
Day2快咗少少，可以睇埋day3甚至day5.

Thanks for the reply.
They are frozen on day 2 as the lab will be closed for 4 consecutive days during CNY.

May I know if a “fast development” embryo indicate low pregnancy rate?

And May I know what the reasons of fast development embryos??

Many thanks and happy new year (emoji)

私人傳訊回覆引用

積分: 9498

6206^#

發表於 23-1-23 08:42 |只看該作者

回覆 Hapi2017 的帖子

Dear Hapi2017,

It’s just too bad the lab has to freeze so soon. But since you only have 2 embryos, I suppose you may transfer both at the same time; and therefore, information gained from further culture is not very useful.

Embryos with fast development can be both a good sign and a bad sign. In young patients, fast embryos tend to give blastocysts sooner, and in older patients, fast embryos usually arrest at cleavage stage and cannot make blastocysts. This is based on general observation in the lab.

Many reasons for growing too fast, I cannot go into too much biology here. In simpler terms, cells have mechanisms (biological checkpoints) to check errors during each cell division before continuing to divide and grow further. When a cell divides faster than usual, there may not be enough time given at each checkpoint. When too many errors have accumulated and cannot be self-repaired, the embryo will stop growing. On the other hand, when there is little or no error to repair, the cells move on quicker.

Back to your case, it is really hard to tell if your embryos are good or not. I have certainly see fast embryos being the winners (make babies), and I have also seen fast embryos stop growing by day3 or day4. For what you have now, you got the best two you can get, be at peace in mind, transfer them after the holiday, and I hope for good news from you.

Best wishes in the Year of Rabbit!
cutecutetown

私人傳訊回覆引用

積分: 1779

6207^#

發表於 23-1-23 13:36 |只看該作者

本帖最後由 Hapi2017 於 23-1-23 13:37 編輯

cutecutetown 發表於 23-1-23 08:42
回覆 Hapi2017 的帖子

Dear Hapi2017,

Dear cutecutetown,

A million of thanks from the bottom of my heart for your reply. Hope my embryos can have proper cell division despite of the rapid growth.

May I ask if excessive mitochondrion is one of the reasons causing embryo rapid development?

Yes I will transfer both of them at a time, hope can have some luck in 2023.

私人傳訊回覆引用

annielo2002

積分: 1675

6208^#

發表於 23-1-23 19:09 |只看該作者

cutecutetown 你好

請問一下，9粒受精，最終有4粒Day 6（5BB,4BB,3BB*2)。其實結果算唔算強差人意呢？我糾結左好耐，點解一粒day 5都無，全部都生長慢….

私人傳訊回覆引用

積分: 9498

6209^#

發表於 23-1-24 07:42 |只看該作者

Hapi2017 發表於 23-1-23 13:36
Dear cutecutetown,

A million of thanks from the bottom of my heart for your reply. Hope my embryos ...

Dear Hapi2017,
I cannot find anything in the literature that relates rapid embryo growth to mitochondria amount. And based on some of my PGT results that provide mitoscore (an index of mitochondrial DNA content in a euploid embryo), I do not see how the amount of mitochondria may affect the speed of development.
Good luck!

私人傳訊回覆引用

積分: 9498

6210^#

發表於 23-1-24 07:52 |只看該作者

annielo2002 發表於 23-1-23 19:09
cutecutetown 你好

請問一下，9粒受精，最終有4粒Day 6（5BB,4BB,3BB*2)。其實結果算唔算強差人意呢？我糾 ...

Hello annielo2002,
9粒受精而有4粒blastocysts 一啲都唔差, 有day5固然好，但day6一樣ok㗎。

私人傳訊回覆引用

eelainee

複式洋房

積分: 306

6211^#

發表於 23-1-25 15:57 |只看該作者

cutecutetown 發表於 10-2-12 11:02
Being in the ivf field for >10 years, I hope to help in a discussion format any of your questions or ...

你好。我今年38歲因多囊一直未懷孕。上星期係台灣首次IVF完成抽卵。當時醫生話會安排將2粒較好既胚胎D3先雪起。其餘就繼續培植後再雪。今日回覆D3*2粒（8A級）D5*5粒（5BB*2粒。4BB*2粒。4CB*1粒）胚胎質量係咪一般？我應唔應該抖一個週期先放胎？同埋順序應該放邊個胚胎先？放胎前多做運動外。有冇咩補充品有幫助？謝謝你

私人傳訊回覆引用

積分: 9498

6212^#

發表於 23-1-27 08:45 |只看該作者

eelainee 發表於 23-1-25 15:57
你好。我今年38歲因多囊一直未懷孕。上星期係台灣首次IVF完成抽卵。當時醫生話會安排將2粒較好既胚胎D3先 ...

Hello eelainee,
看grading胚胎質量是不錯了。
休息一周期先放胎主要是個人選擇，如果抽卵後並未岀現卵巢刺激過度症或其他狀況，接著的周期是已經可以放胎的。
我會先放5BB，然後是4BB, 如果都仲未成功，才會考慮兩個D3同放又或只放一個4CB.
做運動是持久的，不是只在放胎前做一兩天或一兩周；至於補充品，沒有什麼作用，通常女士們都會在預備做IVF前吃，希望可以令卵子質素好些。

私人傳訊回覆引用

積分: 1779

6213^#

發表於 23-1-29 16:40 |只看該作者

cutecutetown 發表於 23-1-24 07:42
Dear Hapi2017,
I cannot find anything in the literature that relates rapid embryo growth to mitocho ...

Thanks again for your reply

Just curious, may I know if you have seen any correlations between level of mitoscore and euploid embryo?

Wonder if euploid embryos usually have high mitoscore too?

Many thanks in advance

私人傳訊回覆引用

積分: 9498

6214^#

發表於 23-1-30 11:32 |只看該作者

Hapi2017 發表於 23-1-29 16:40
Thanks again for your reply

Just curious, may I know if you have seen any c ...

Dear Hapi2017,
Mitoscore is not widely used because the evidence for it being useful is not very strong. The idea is that euploids that will implant usually have low mitoscores. From my experience, it is generally true, but I don’t see a magic number above which a euploid will absolutely not implant.

私人傳訊回覆引用

cc_2021

積分: 1611

6215^#

發表於 23-1-30 18:02 |只看該作者

Dear cutecutetown

你好，我上年透過PGT-SR成功生左第一胎～
之後一直全人奶餵BB, 所以仲未黎M…
我黎梗想收奶，黎M後再放胚胎(emoji)(emoji)～

想請教一下，有無話停人奶後，等幾多次經期，先會令身體荷爾蒙好啲，放胚胎成功率高啲？

因為聽講停人奶後，經期會比較亂，我自己諗會否第二次經期後放胎，會比較穩陣？

(PS：剩下一粒5AC正常胚胎）
謝謝你！

私人傳訊回覆引用

積分: 9498

6216^#

發表於 23-2-1 02:45 |只看該作者

cc_2021 發表於 23-1-30 18:02
Dear cutecutetown

你好，我上年透過PGT-SR成功生左第一胎～

Hello cc_2021,
你可以先來一次經期，再約見醫生看看怎樣安排時間放胎。你是想用自然周期放胎嗎？其實停人奶後周期亂唔亂都因人而異，如果你之前是用自然周期成孕，可能都偏向用番，那就要看來一兩次經期。但如果用人工周期，就讓醫生看看指數便可知會否適合最快時間放胎。

私人傳訊回覆引用

cc_2021

積分: 1611

6217^#

發表於 23-2-1 07:22 |只看該作者

本帖最後由 cc_2021 於 23-2-1 07:22 編輯

cutecutetown 發表於 23-2-1 02:45
Hello cc_2021,
你可以先來一次經期，再約見醫生看看怎樣安排時間放胎。你是想用自然周期放胎嗎？其實停人 ...

Dear cutecutetown

謝謝回覆，我上一次係用自然週期喔，我自己都想用番自然週期，唔想用咁多藥～

但因為我係公家症，唔係咁容易約見醫生，或者我等第二次經期，才找他們安排放胎，也許要抽血和照usg 才知道身體狀況，希望下次放胎一樣幸運

私人傳訊回覆引用

shirleybbking

洋房

積分: 31

6218^#

發表於 23-2-1 10:00 |只看該作者

cutecute town 你好啊

我舊年11月放咗個解凍胚胎Day6 5AB，已經check左NPS。之後一路保胎塞同食藥過左12周，但系13周bb無咗心跳。請問是否同停藥有關？如果唔系係咪即係我身體原因？要做d咩檢查？麻煩你。宜家日日喊。

私人傳訊回覆引用

積分: 9498

6219^#

發表於 23-2-2 05:12 |只看該作者

cc_2021 發表於 23-2-1 07:22
Dear cutecutetown

謝謝回覆，我上一次係用自然週期喔，我自己都想用番自然週期，唔想用咁多藥～

Dear cc_2021,
公家仲簡單，你打電話去問一問姑娘，如果想放胎、剛停咗人奶要點做，她們應該可以給你些意見/資訊，甚至可以排期。我也不清楚要否等很久又或下次來經便可開始，但起碼心裏有個預算。
祝好運

私人傳訊回覆引用