I used to have acne every month, especially around period ... mostly around my nose and chin.
I have tried using "Demra-Rx Comedone Formula" since February. To my surprise, I haven't got any breakouts since then. It really works for me. I know it's available at some doctor clinics (general practice). No prescription is needed. It costs about $400 per bottle, enough for 4 to 6 months.