15. Are the pneumococcal vaccines, PCV7 / PCV10 / PCV13 and 23vPPV, interchangeable?
No. Vaccinees should receive appropriate type of vaccine according to their age.
我自己search WHO(世衛) paper,7價和13價同廠,PCV7 is designed to be interchangeable with PCV13 at any point in the vaccination schedule. 即係primary dose series打7價,可用13價booster(加強劑)完成。世衛paper指出,有研究顯示7價transition to 10價,冇影響7價發揮成效;但冇足夠研究證明10價primary serise+13價加強劑接合有冇效。
所以研究顯示,最好的接種方法,係4針打哂13價 (3 dose of primary series + booster),或7價接13價(at least 1 PCV7 and/or PCV13primary + booster)。否則,保守派醫生會建議先完成整個7價或10價的接種(primary+booster)再打13價booster。