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男爵府

積分: 9496


6261#
發表於 23-4-15 14:58 |只看該作者
Wisdomjj 發表於 23-4-15 00:33
Dear cutecutetown
剛放了一粒4cc(pass Pgt sr), 胚胎學家當日同我講 話胚胎解凍左一小時就脹左6成 好有 ...

Dear Wisdomjj,
沒有特定要澎漲多少的,有時都要給點時間。因為在冷凍時囊胚會收縮,解凍後必然會澎漲回原形;這過程有的快有的慢,能夠在短時間內看到是一個好現象,証明胚胎在蘇醒,應該會繼續成長吧。希望好快聽到你的好消息!


複式洋房

積分: 465


6262#
發表於 23-4-15 20:03 |只看該作者
回覆 cutecutetown 的帖子

Dear cutecutetown Thank you so much ❤️我都希望有好消息 我pass test 嘅都係4cc 🤣


複式洋房

積分: 414


6263#
發表於 23-4-16 00:59 |只看該作者
cutecutetown 發表於 23-4-11 09:06
Hello gracet0_0,
你的情況不是靠中醫可以改變得來,是時候進取一點找個IVF 醫生。但醫生可能亦會看看你有 ...

多謝你既意見!等我下星期book醫生做多啲檢查先!


大宅

積分: 1422


6264#
發表於 23-4-24 21:54 |只看該作者
dear cutecutetown,

我老婆想今個周期放胎,
LMP 14/4

醫院安排今日24/4 九點抽血
下午3點就話驗血顯示已排卵,所以明天唔洗再返去抽血
P4 1.7
LH 20
E2 千幾
卵泡 18
姑娘即刻安排30/4放DAY6雪胎

我明白P4只要大過1就代表已經排卵
想請問:
1. 我好想知, LH 同E2點睇到係今日排卵,而唔係尋日?
2. 如果真係尋日排卵, 30 /4 才放DAY6 胎, 會否有影響?

謝謝


男爵府

積分: 9496


6265#
發表於 23-4-26 03:51 |只看該作者
billykhw 發表於 23-4-24 21:54
dear cutecutetown,

我老婆想今個周期放胎,

Hello billykhw,
1. 判斷排卵與否是看LH升跌,不是單憑一個數值。所以醫生是根據早兩天的LH和24/4的LH,對比下知道已排卵。E2提供了有關那個在自然周期發育的卵泡是否成熟,一個成熟卵泡大概會產生1000左右E2,加上照到18mm, 即成熟,所以跡象是排卵了。
2. LH surge跟我們IVF抽卵前打的排卵針大義上相同,所以你太太是23/4 晚surge,如果這等於排卵針,那就是25/4抽卵,固day5就是30/4。放凍溶的囊胚,無論雪時是day5或day6都會以day5作放胎時間。
放雪胎的timing是IVF醫生的基本知識,所以應該不會有錯的,不要擔心。


別墅

積分: 644

2026勳章


6266#
發表於 23-4-27 17:15 |只看該作者
Hello 樓主

上次問過你意見之後,我換咗醫生再抽咗兩次卵。兩次胚胎共有11粒,全部都去到Day 5、6做PGS,4粒mosaicism,7粒Aneuploidy。
醫生話如果我想試放胎,首選係一個-21m(40%),+5sm(63%)嘅胚胎。

想問問:
1. 香港有呢方面嘅醫生/專家可以諮詢嗎?因為我在外國做IVF,所以想喺香港了解清楚先
2. Mosaicism嘅胚胎係咪大多唔會建議用?

Thank you


大宅

積分: 1422


6267#
發表於 23-4-28 15:16 |只看該作者
回覆 cutecutetown 的帖子

dear cutecutetown,
多謝你教我睇呢D數字
因為醫院23/4冇幫我太太抽血
第一日見醫生就突然話已經排卵
所以好怕醫院亂黎,浪費左珍貴既胎(瑪麗公家)
畢竟太太40歲, 只有三個DAY6胎

去年十一月第一次放胎
食了兩次排卵藥
一共抽左12日血(即DAY27)先告知有排卵
可惜
就是失敗,沒有著床

今次LMP 14/4
16/4食排卵藥五日
24/4第一次見醫生(DAY10)同日安排放胎日子30/4


可以幫我看看呢D抽血數字
到底我地應該跟醫院指示30/4放胎,還是等多一個月?

23/4 沒有抽血

24/4 LH 20.8, P4 1.7, E2 1096 ,內膜11.9, 卵泡18

25/4 LH 34, P4 5.幾 ,E2 5百幾 ,沒有任何檢查

26/4沒有抽血,決定30/4放胎


謝謝你


男爵府

積分: 9496


6268#
發表於 23-4-29 03:54 |只看該作者
Emma_M0n 發表於 23-4-27 17:15
Hello 樓主

上次問過你意見之後,我換咗醫生再抽咗兩次卵。兩次胚胎共有11粒,全部都去到Day 5、6做PGS,4 ...

Dear Emma_M0n,
介唔介意講你响邊度做ivf? 你才36歲左右,但只有mosaic沒有正常,很少遇到。而响邊度做、有沒有PGT result在手,亦可能在諮詢方面有限制。
1. 你要找genetic counselor做諮詢,但要找些略懂IVF的,因為我見過有些不理解的會把事情當成你已跎著一個mosaic fetus(胎兒)去說,意見並未對題。
2. 通常唔建議用,但最近文獻還是有研究指出若mosaic level低是沒有影響懷孕率和BB出生後是完全健康的。
其實一切都要看你可接受多少風險和會否考慮再抽卵。


男爵府

積分: 9496


6269#
發表於 23-4-29 04:41 |只看該作者
billykhw 發表於 23-4-28 15:16
回覆 cutecutetown 的帖子

dear cutecutetown,

Dear billykhw,
跟醫院指示是可以的。
雖然23/4並沒有LH作參考,但LH升後E2會跌,而P4亦會開始升,加上24/4亦看到成熟卵泡,它和當日的E2吻合,所以各方面都看到30/4要放胎了。
始終已40歲,加上是day6胚胎,不成功多與胚胎有關。若果今次不成,下次可以考慮用人工周期。


複式洋房

積分: 496


6270#
發表於 23-4-30 13:08 |只看該作者
Cutecute town

妳好,我剛剛4月在台灣抽卵,今年39歲,我老公40歲, 我D2 FSH 13.23, AMH 1.26, 結果抽到6粒,4粒為GV, 2粒 d3 係8b/ 9B.

Day5 時一粒3CB,做了pgs,原本想截止唔做PGS, 但最終實驗室做了PGS😭一粒桑葚胚,day6 變為2CC, 我要求台灣不做pgs,怕原本級數已不好,做pgs會損耗,而這結果都令我好傷心失望。

我11/2021 在香港私家做IVF, 當時一粒day 5 3AC, 3粒day 6 5AA,4BB, 5BA, 結果10/2022成功 懷孕到12週停心跳,但藥流唔清,做了2次刮宮手術+中covid.

想問問,我這情況
1.若day5 3CB (day5 下午時間)唔過pgs, 就不用放胎;若過,是否都值得放?
2. 而day6 2cc (day6 上午時間)我知道級數好差,故無做pgs, 請問這個又值得放嗎?若成功懷孕,流產率或缺陷風險好高?
3.這次抽卵結果是否很差,6粒有4粒GV,其他級數也不好

因為經濟能力,我們只能第二次選擇係台灣做ivf,只當買個希望,我和先生也傷心,已決定放棄再做ivf,始終經濟能力也考慮,或我們再嘗試。謝謝妳!




洋房

積分: 39


6271#
發表於 23-4-30 13:50 |只看該作者

please help to delete the post, thanks

本帖最後由 wendykocw 於 23-4-30 14:08 編輯



大宅

積分: 1422


6272#
發表於 23-5-1 21:29 |只看該作者
cutecutetown 發表於 23-4-29 04:41
Dear billykhw,
跟醫院指示是可以的。
雖然23/4並沒有LH作參考,但LH升後E2會跌,而P4亦會開始升,加上24/ ...

多謝你呀,我(老公個account已被我徵用)睇完都安心唔少
琴日順利放左胎
而家要忍住唔驗


男爵府

積分: 9496


6273#
發表於 23-5-2 06:49 |只看該作者
BuckBuffy 發表於 23-4-30 13:08
Cutecute town

妳好,我剛剛4月在台灣抽卵,今年39歲,我老公40歲, 我D2 FSH 13.23, AMH 1.26, 結果抽到6 ...

Dear BuckBuffy,
1. 如果PGS pass,當然值得放!
2. Day6 2CC no pgs, 不值得放,假如放了又懷孕,估計流產率很高,缺陷風險更不用說。
3. 有了你在香港11/2021的一次作比較,今次算是差了。
但你說10/2022成功過,那次已是用了最後一個胚胎?如果還有胚胎剩,可以放啊!


男爵府

積分: 9496


6274#
發表於 23-5-2 07:05 |只看該作者
billykhw 發表於 23-5-1 21:29
多謝你呀,我(老公個account已被我徵用)睇完都安心唔少
琴日順利放左胎
而家要忍住唔驗

Dear billykhw(太太),
千祈唔好太早驗,棧嚇親.
呢兩個星期放鬆心情,不要在意有冇徵兆,因為有或無亦沒有確定性,很多時都沒有徵兆的。不要理會有冇來M感覺、谷住谷住、著床血etc,以上種種有沒bingo的人都曾經說過自己有或冇,同擲公字一樣,係50/50 (>v<)
保持心情開朗,多休息,找些事情分散一下自己注意力,多想無益。祝好運


複式洋房

積分: 496


6275#
發表於 23-5-2 11:19 |只看該作者
回覆 cutecutetown 的帖子

Dear Cutecute Town
謝謝妳回覆呀&#128591;&#127995;

1.明白,禱告希望神保守pgs結果&#128591;&#127995; 同樣想問問,day5 上午2CB, lab通知下午為3CB, 為何不等day6 發展才冷凍? 我怕3CB 做pgs 會好傷害本身grading已好差囊胚,但lab表示當日day5 下午已變3CB , 故沒有再聯絡我們便做pgs

2. 明白,day6 2cc就唔好放,唔想傷身又傷心,又怕bb唔健康&#128591;&#127995;但想問問,為何lab 不等埋day 6下午,看看囊胚發展才冷凍?可能到時囊胚有變化?

3. 明白,可能年齡,運動或不同地方做ivf, 效果不同,我也體會台灣做,未能按監察卵泡情況調整打針的份量或轉其他,這也是很無奈的情況,但衡量在香港的價錢和台灣價錢,不得已的選擇&#128591;&#127995;

4.在11/2022的已放晒最後的囊胚,當時day6 4bb 和day 6 5ba(1PN), 最後成功懷孕到12週多停心跳,藥流不清下做2次刮宮,所以在香港已沒有囊胚&#128591;&#127995;

謝謝妳呀,由於經濟情況唔許可,或者日後我和先生都係放開啲,順其自然,雖然真的好難過,謝謝妳的回覆和給予建議&#128591;&#127995;☺️


男爵府

積分: 9496


6276#
發表於 23-5-3 03:30 |只看該作者
BuckBuffy 發表於 23-5-2 11:19
回覆 cutecutetown 的帖子

Dear Cutecute Town

Dear BuckBuffy,
1. 3CB已可以做活檢,唔一定要等day6;如果等day6會有兩個風險,首先個胚胎可能會變差咗就不合格做PGS, 又或長到hatched階段,活檢比較有難度之外,這個階段的囊胚在冷凍後的存活率有機會差一點。
2. Day6 2CC其實生長速度不達標,質素亦只cc, 就算到下午都很難有cb 或bc;但為什麼實驗室會不做PGS但又把它雪起我就不清楚了。
3. 明白的,所以我從不建議jm去台灣。
4. 看看今次3cb的結果吧,可能有機會呢。
能夠放開、順其自然是好事,真的有jm是這樣反而就自然中奬。雖然不是每個都能這麼幸運,但神往往有祂的安排,願主眷顧和祝福你


複式洋房

積分: 496


6277#
發表於 23-5-3 18:18 |只看該作者
回覆 cutecutetown 的帖子

Cutecute town
謝謝妳經常的鼓勵、說明,縱然我們未見過面,祝福妳和所有JM都平安順利,心願達成&#128591;&#127995;☺️

點評

cutecutetown    發表於 23-5-4 05:18


複式洋房

積分: 132


6278#
發表於 23-5-3 23:12 |只看該作者
Dear cutecutetown,

Thank you for your support here first.
Few questions RE) IVF oocytes retrieval
1.) I'm 39yo going to be 40 soon this year AMH 4.44pmol/L
2.) I did my first oocytes retrieval at age of 34. 2 rounds I have got total of 21 oocytes and 19 were mature
3.) Did my first round of IVF last year in Dec: only 4 embryos made it to Day 5 PGTA . One normal XX but XY complex mosaic (46 +5+15-7-9)
** my doctor stated that the sperm motility was poor : 46% pre wash and 100% post wash (?? why)
4.) I did another round of oocyte retrieval in April 2023, got total of 17 occytes, 13 were mature. 8 of them made it to Day 5 PGTA. Still XY complex mosaic/ abnormal
( 46 +14; 45-15, 46+1+15 +X-Y, 46-18)
** this time the sperm motility is dropped from 59% pre wash to 48% post wash ??why again

My questions are
1.) Sperms quality is poor but why motility improves after post wash in the first round
2.) sperm quality is poor still second round? (I have changed my sperm donor already)
3.) I have performed a genetic test on myself and both the sperm donors as well. What happened here why all my XY embryos has problem please?
4.) I have discussed my case with my gynaecologists, they won't recommend using these XY embryos. What should I do to improve it ?
5.) Planing to start all over again in September this year. What else do I need to look for?

I am sick of injecting myself. So wanna give up. So depressed now. Thank you.


男爵府

積分: 9496


6279#
發表於 23-5-4 08:18 |只看該作者
回覆 Francesac 的帖子

Hello Francesac,
I will give some comments for the info you provided, and then I will address your questions in a separate message.

1. Your AMH level of 4.44pmol/L is very good for your age group; that's why you still have a decent number of eggs retrieved last month.
2. You mentioned your 1st oocyte retrieval was at age 34. I am confused about "2 rounds"; so you had 1 time or 2 times of oocyte retrieval? Also, did you have all the 19 mature eggs frozen?
3. I am also confused when you described your first round of IVF in Dec 2022. Did this round in Dec involve an egg retrieval, or you had your frozen eggs from age 34 thawed and fertilized? Also, from the result "one normal XX but XY complex mosaic (46 +5+15-7-9)", this one embryo is not normal at all. Is this result stated differently on the actual PGT report? What about the results for the other 3 embryos?
**Pre wash is when the sperm is in its original state; the assessment is part of the semen analysis. When we "wash", or process the sperm for further use in IUI or IVF, the sperm sample will be undergoing a "wash", or treatment with centrifugation, to concentrate the motile sperm. So it is not unusual to have a post-wash motility of 100%.
4. I am again very lost looking at the results you stated (46 +14; 45-15, 46+1+15 +X-Y, 46-18). Are you trying to show me the results of all 8 embryos that made it to Day5 PGTA, or is this one single result for one of the 8 embryos??
**sperm motility alone is not the only factor causing aneuploidy, or abnormal embryo. Sometimes, even after sperm wash, sperm motility may not improve or even become worse. But for most PGTA cases the lab performs ICSI (IntraCytoplasmic Sperm Injection) to fertilize the eggs, sperm motility is almost irrelevant as long as we can find motile sperm.

I shall attend to your questions in the next reply.
cutecutetown


男爵府

積分: 9496


6280#
發表於 23-5-4 08:51 |只看該作者
回覆 Francesac 的帖子

Hello again Francesac,
1. I have explained what a sperm wash is in my previous reply.
2. You changed your "sperm donor"; do you mean you actually used donor sperm, i.e. sperm samples that are donated from someone who is not your husband or sexual partner, or you simply mean you changed husband/partner? Since you have 2 different sperm donors in the 2 rounds of IVF, sperm motility and/or quality will unlikely be the same.
3. XY are only the sex chromosomes, while you also have 22 pairs of chromosomes. Half of the chromosomes in an embryo come from you and the other half from the sperm donor; so, if either the sperm or the egg does not carry the correct number of chromosomes to begin with, the resulting embryo will not be normal. And even if we start with a correct number, there is still chance for errors during cell divisions of the embryo. The underlying reasons for having such errors are numerous, but the most common one is related to the woman's age.
4. I will not recommend using those abnormal embryos. And it seems that you are only interested in the embryos carrying XY, i.e. you want only male embryo(s)? There is not much you can do to improve because even after you have another sperm donor, your embryos are still aneuploids; so the problem is more likely to be of female origin, and given your age, it is not unreasonable to assume many of your eggs may already be aneuploid to start with.
5. From an optimistic point of view, you have a good AMH level and every time you have a good number of eggs. You may have to undergo a few more IVF than other younger women in order to find a euploid male embryo. Since you are trying to fight against time, and if financially feasible, I will suggest you start your next IVF sooner.

I am curious where you are from and where you did your IVFs. You do not appear to be doing all these in Hong Kong.

Good luck,
cutecutetown


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