I have a quick question! I did my IVF process at the public hospital and froze 6 day-5 blastocysts. I'm planning to do egg retrieval in early Feb. The doctor did not mention that I should do PGT, so I did not do it. I think that's because my husband and I do not have genetic diseases. Are there any risks with not doing PGT? Or are all of the diseases detected via PGT will usually be detected during the usual pregnancy scans?
Hello nini920902,
You have already got 6 blastocysts; did you really mean "egg retrieval in early Feb", or embryo transfer in Feb?
By PGT, we often mean PGT-A, which is Preimplantation Genetic Testing for Aneuploidy. This is to see if an embryo has the correct number of chromosomes. Aneuploidy, or having an abnormal number of chromosomes, affects embryo implantation and thus, success rate. An example of aneuploidy is trisomy 21, or Down Syndrome, where there is an extra chromosome 21. Screening/detection of aneuploidy can be checked during pregnancies, by ultrasound or blood test. One note is that both parents almost always have normal number of chromosomes; in other words, none of the parents have genetic disease and yet the embryo may still have aneuploidy. Aneuploidy is usually associated with the age of the woman; the older she is, the higher her chance of having aneuploid embryos.
PGT-A is not yet proven useful in all patients of all ages, and in a public hospital, you need to at least fall under the right criteria before the doctor will offer it. Also, whether you are a public or a private patient, you always have to pay for PGT-A.
A quick note on diseases, if you or your partner has a known genetic condition, PGT is also available. In such case, the embryo will be tested such that only embryo(s) unaffected by the disease condition will be transferred to the womb.
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