Using your own natural cycle, right? Your body is ready, a bit of luck and at least one good embryo with potential will get you there.
See if you will have a chance to discuss with your doctor about assisted hatching. Perhaps you may want to give the discretion to the lab so that if they find the wall thick, they can simply go ahead and hatch. In other words, if the embryos don't have thick walls, the lab won't do the extra procedure and you won't be charged the extra fee. (I am just making a suggestion here; the policy of your doc or the lab may ask you to simply give a yes or no instruction.)
Many women do ask about why they have progesterone support for fresh ET but not in their FET. To save the women from worrying (without knowing the biology behind) and for easy management, doctors will just give progesterone anyway. The dosage is reasonably safe, and the simple fact of receiving medication makes many patients happy. (Many feel more comfortable when they are prescribed with more medication than they actually need; just see how many flu medication you are given when you walk out from your private GP's office.)
Same idea when you are given both vaginal inserts and shots. It is proven in many scientific studies that you only need one or the other, not both; but doctors are stubborn and patients are happy, and of course the happiest is the drug company :) As long as the dosage is biologically safe, I suppose it doesn't matter?!
One thing you do need to be aware of. I am not sure if you are allergic to the oil adjuvant of the progesterone shot; I have seen a fair porportion of women develops the same. Bruises and mood swings are not needed (they are the side-effects). If you can cope, good luck; but you should at least inform your doctor about the local reaction (of your skin to the injection) and see if the oil base of the shots can be changed, or sometimes a higher dose of the vaginal insert will be given.
It is a little funny that while you obey and trust your doc 110% with no question at all, mother2be was so doubtful about her doctor's every move. Take care,
cutecutetown
點評
mother2be
I had no doubt with my doctor the first time. But doing it a second time, I am a lot more cautious as my affordability to losing the chance is getting lower.
發表於 11-5-16 10:46
It's been five days after I did the ET on Monday. My tummy is not feeling well, very much bloated and every other day got mild diarrhea. A lot of the times just after I ate something, all my intestines are like pulling together, painful.... and then I need to rush to the tolilet. Shall I tell my doctor?
I tried IVF in 2006, failed one time and FET in the same year and got my daughter. 3 years later in 2009, I did another FET, got preg but then the baby stop growing in the 9th week... But as far as I remember, I didn't feel so uncomfortable before... is it becoz of aging problem?
Anything I can do to sooth the pain and the twisting intestines?
I just saw my doctor during lunch today to prepare for my FET. I told him about the progesterone shot and he just said a lot of women experience the same side effects and he would still recommend me to have the injection post transfer unless i feel the side effects are getting too severe.
I have 3 day 2 4 cells (both grade 2) and 2 day 3 6 cells (grade 2 and grade 2-) frozen. Initially my doctor suggested to thaw 2 day 2 embryos first and transfer on the same day for this cycle. If no success, then i can thaw the remaining day 2 overnight and transfer together with the day 3 embryos for the next FET. In that case, i will likely have 2 chances of FET.
However, i told him i want to maximize my chance of success for this transfer instead of getting comfort that i can still have another FET in case this one fails. He then suggested that i can thaw all 3 day 2 embryos and observe overnight. If less than 2 survive on day 3, then he will thaw the remaining day 3 embryos and put back all i got in once. In that case, i might not have anything left for further FET but this should maximize my chance for this cycle. Do you also agree with this approach or you have any other suggestion?
I met doctor today and discussed with her on assist hatching. She mentioned that she would only advice women with multiple failure or thick wall. She said my embryo walls were not thick and she did not suggest me to do so. She mentioned that there was no concrete figure on assist hatching helps implantation. Do you agree?
I'll FET on either next Wed or Thur, I will put 2 embryos with 9-cell grade 1- and 12-cell grade 1-. My doctor is confidence on me...and I should trust her. I saw many successful cases in the clinic.
Thanks for your advice ar...
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cutecutetown
Likewise, I am confident with you. Remember all the "tricks" emptying your bowel before ET to avoid anxiety and excess bowel movement; also the tips for your 心急 factor. Do not "貓貓燒鬚"
發表於 11-5-13 23:34
Please tell your doctor, your upset bowel is probably not just an ordinary diarrhea to me. It could be some bad bacteria that are more virulent than the regular type, or you are getting too nervous & having an easily irritable bowel. Was your ET with fresh or frozen embryos? Your bloated tummy seems unusual as well. Seek some real medical help from your ivf doctor and he/she will give you appropriate care.
Aging won't cause diarrhea; first thing you need is to see your doctor. I am sure he/she will at least give you a quick look, from there on, you probably need to stop worrying. I think your pregnancy history made you feel that you have to succeed, which in turn put extra pressure on you. There is nothing wrong with you. When you see your adorable daughter, you know she is a gift and if she will have a brother/sister, that is just 錦上添花. Your daughter will still love you the same whether you give her a sibling or not. Take care of yourself.
Regarding the same side effects of a lot of women seeing your doctor, I simply feel very bad for you and all of them. It is like telling you to live with the side effects......I can't believe that's the best he can offer......
At least the thawing strategy is sensible; I don't want to suggest other alternative.
I've been reading this thread for a year now and it's very informative. Thanks for you efforts for guiding people like me.
Finally, I've committed to IVF this cycle and I just had by ET today. 13 oocytes were retrieved 3 days ago. But only 4 of them were able to be fertilized. Out of these 4, there's 1 8 cell Grade 1, 1 8 cell Grade 2 and I have had a ET for these 2 today. For the other 2, the embryo specialist told me there're only 2-4 cells and most like they won't be able to develop. Thus, she didn't recommended us to freeze them now.
She also told me there are some dark, central spots in my other eggs (6-7 of them) which means they are eggs of poor quality. I'd like to ask is this normal for women of my age (I'm 34)? Is there any way to improve egg quality? and lastly, does it mean that if I attempt another oocyte retrieval in the future, I'll have a similar number of fertilized eggs?
Do you know if all your 13 oocytes were mature? Did you get IVF or ICSI? How's your hubby's sperm like on that day?
Also, while you were on stimulation, did you have nasal spray or Cetrotide? How many days of hormone injection (e.g. HMG, Gonal-F) you had before getting egg retrieval? Perhaps there are a few more pieces of info that may be useful, but don't worry if you don't know.
For the dark central spots you mentioned, I guess I somewhat know what your embryologist meant. The spots are not very common (but not rare either), and when they occur, usually only a small portion of the whole lot of eggs will have them. If you will consider another IVF in the future, the spots may still occur in some eggs. As for fertilization rate, I am hoping you should probably get a few more fertilized, especially if you return to the same doctor and same lab.
Unfortunately, there is no simple solution to improve egg quality. Although there is no scientific proof to my theory, I believe that egg quality is somewhat predetermined, and it is what you/we could do to make the ovaries to recruit the 'better' eggs for that particular ivf cycle (I assume you've read my past postings about egg recruitment in each menstrual cycle). There is simply no quick-fix, and my belief is that if you have an overall active and healthy body, all body mechanisms should be at good performance. As always, I recommend moderate exercises (as a habit rather than a one-week short program); this will improve blood circulation, which in turn flushes out wastes and toxins. Improved blood flow will hopefully enhance your ovaries (....where eggs are recruited) and uterus (...where an embryo should implant and grow there for 9+ months), and in the long run, your heart and lungs also benefit. So, there is nothing to lose really by starting a healthy lifestyle today.
I know a lot of jm's are already eating healthy (low sodium, low sugar, low fat, etc etc.). And it needs to be balanced too, don't overload your body with herbs and supplements. Be good to yourself as well; allow yourself to slow down sometimes, enjoy a cup of ice cream or relax watching a movie.
I had started my 2nd IVF attempt when I last wrote to you. I shared with you my worry that my doc may give up on me if I fail this time which came up to be true. I failed and have just seen my doc. She said the main problem is still the quality of my egg (my uterus condition is perfect and although my hubby's sperm quality is poor in all aspects, it is still qualified for ivf). She recommended me to take DHEA for 6 - 8 weeks and see. She said if I choose not to take this supplement, there is no point to keep trying. Now that I have got 2 Qs in my mind.
(1) I have got 11 eggs retreived in this cycle and finally only got 2 embryos transferred in Day 2 - 1x4CG2+ and 1x4CG2- with no embryo frozen. Would you think my case is that worse?
(2) Would you suggest me to take 2nd opinion from another doc?
What I think is I will turn 40 in 4 months time and need to act quick....if chance is still there.
i will try my fet this cycle and start the blood test (checking Ovulation)
on 23/5(day11).
i want to ask:
1. my doc will thaw 1 12-cell embryo only.如果個embryo溶雪後唔用得, 係咪一定要等下個CYCLE 先可以再FET? 可唔可以即刻為其他餘下既embryo溶雪, 咁咪可以即刻放embryo at the same cycle, no need to wait for the next cycle?
2.有嚴重子宮內膜異位既人成功著床既機會會唔會比正常人低呢?
Hi Cutecutetown
Thanks for your detail reply. To answer your questions,
Do you know if all your 13 oocytes were mature?
----> I was told around 10 of them were mature.
Did you get IVF or ICSI? How's your hubby's sperm like on that day?
---> I got IVF only and the embryologist told me his sperm quality was OK (Motility / Quantity OK, morphology 11%)
Also, while you were on stimulation, did you have nasal spray or Cetrotide? How many days of hormone injection (e.g. HMG, Gonal-F) you had before getting egg retrieval?
---> I was on a short protocol only and took 225mg Gonal-F for 8 days before egg retrieval. And my LH on day 7 was 1.24
Yes, I exercise regularly and prefer having veggie meals. My hubby said I might not have enough proteins in my diet. Would that help?
Your doctor didn't give up on you, she just asked you to take DHEA for ~2 months.
(1) From your previous postings, you had ivf instead of icsi, correct? How many fertilized in each ivf attempt (out of the total no. of eggs you had)?
(2) You may do so, but getting treatment from another doc may take longer than you think.
cutecutetown
點評
siushuk
PM you the info. Much appreciate your thought. Thanks Thanks!
發表於 11-5-16 21:43
1. You have many embryos in storage, and this is your first time ever having an embryo transfer procedure, right?
Your doctor probably meant that you will have one embryo to put back into your uterus this time. As we only aim for one embryo, you will have the best one (the 12-cell embryo) thawed out. Working in my lab (and I believe all labs do), if an embryo doesn't survive the thawing, I will immediately thaw another one. So, you won't need to wait for the next cycle :)
2. I don't think so, endometriosis (子宮內膜異位) has more negative effect, if such effect is present at all, on egg quality rather than the womb. Especially your doctor has measured and monitored the endometrial lining all long, you should not worry.
[Now I just realize the Chinese name of endometriosis probably made you think that the lining will be abnormal somehow; that name is a little misleading...]
In natural cycle FET, you won't need vaginal inserts nor injections. For details, you may read postings #998 and #1002. A short summary --> your doctor will decide, sometimes balancing biological need with management ease. Purely biology speaking, in natural-cycle FET, no need for luteal phase support; in fresh IVF-ET, yes, and as luteal phase support, 塞藥 is good enough in most cases.
It could be just the egg quality this time. Don't get too disappointed yet, you had the 2 best embryos transferred. If they both have the potential, I am afraid you may have to worry about having twins. While not getting our hope too high, in my patients who have 2 good-grade 8-cell embryos for ET, a good chance they will bingo, whether they have extras to freeze or not. Practically speaking, in among the same cohort of eggs retrieved, you only need one or two good ones to give you a baby or two. If you have more of such good ones, that's bonuses; but you need to pay for their storage. If you have none and if only we could "predict" ahead of time, you rather have a new cycle sooner. Given you the best and worst scenarios, I think you are still in among the average group being more on the good side.
A little comment on your veggie meals. If you are not a vegetarian for whatever reason(s), try to have good-quality proteins. It just so happened that one of my friends, who has been a vegetarian for >20 yrs, reverts to eat some meat now because she is badly deficient of vitamin B12 and some others. She is now back on fish and some chicken. There are many "vegetarian" protein sources, such as eggs, beans, soy and dairy products. However, I do exercises regularly and like veggies as well, and I find that when I don't have much meat or eat mostly carbohydrates + vegetarian meals, I am more exhausted after exercises. The "tiredness" is manageable, but there is something missing, if you know what I mean. I guess our muscle mass needs meat-proteins to sustain?! So, even if you don't really like meat, try to have some fish, shrimp, crab, or lean chicken.
How does that relate to fertility? Not sure really, but if your overall body is not deprived of anything for survival, it will devote its time to reproduction......just logical.
my chi doctor asked me to have blood test about AMH. Do you know what is it and where can i do this test?
點評
cutecutetown
I don't think any ivf centre in HK has AMH as its routine test.
發表於 11-5-16 12:36
cutecutetown
Anti-Mullerian Hormone (AMH) is one of the predictors for ovarian reserve. It is still not as common as the measurement of day3 FSH, which has been the "traditional" parameter to check the same.
發表於 11-5-16 12:35
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