thanks for your information. just wondering if i failed FET, when will my M come? will it only come after i stop using vaginal progesterone and progesterone injection?
another biology question, if was given E2 in this FET from start until even after FET. just wondering what is the use of E2 in the whole process?
noted that in this post, you mentioned that the pregancy test usually to be done 14 days after ET. but my doc count the date of doing pregancy test to be 14 days after ovalution, therefore 9 days after my Day 5 embryo FET. is it too early which may cause the result not accruate?
also, i noted that ICSI may have some abnormalities in the bb, whcih may be due to bad sperm quality. what kind of abnormal will be passed to bb in such case? actually, i had icsi because my hubby's sperm quality is not good (not moving fast and not enough quantity) but i was not being told of the abnoralities. therefore, would you advise on that. thanks.
If you usually have regular menstrual cycles, and if you fail FET, your M will come around the time when you should have your menstrual cycles. However, if your cycles aren't very regular, once your bingo test is negative, progesterone can be stopped and M should come in a few days or in a week or so.
Your FET is a hormonal replacement cycle, the name is self-explanatory. Hormones are used to replace or simulate your natural cycle (i.e. the whole cycle), not just the first half.
The "14 days after ET" is what most clinics do; because (i) it is easy to count (ii) the result will be more definite. The rule dated back to times when most patients had ET on day1 or day2. Since you have D5 FET, the wait time can be a little shorter, and in the case of a bingo or a weak bingo, the doctor will also have ways to ascertain the result (obviously not by home pregnancy kit).
Note on ICSI. While bb derived from ICSI may have some abnormalities, we are talking about cases where the sperm is very poor (severely compromised in quantity, motility, and/or morphology). In those cases, world figures said a ~5-6% chance as compared to natural conception (i.e. normal sperm) of ~2-3%. [I may not have quoted the exact correct %, but the % is very low.] It's hard to describe all the possible abnormalities because some can be easily explained by basic genetics (e.g. microdeletions in the Y chromosome will pass on to the son), but some have to go into epigenetics and imprinting (too heavy on biology, I simply can't do it in this thread). In short, similar abnormalities will also occur in natural conception but at a lower occurrence. The more common abnormalities e.g. cleft lip and palate (兔唇裂顎), others are rarer but may have a link to ivf/icsi e.g. Angelman syndrome (安裘曼氏症). I have to reiterate that these happen but rarely, in case you start looking them up on the internet and get over-worried.
Nowadays a lot of clinics are offering ICSI to all patients, regardless of sperm quality. The technology itself is likely safe in trained hands, and we try our best to pick the "best-looking" sperm to be placed into an egg.
thank you very much for your information. you seemed stay up late to handle my question, really sorry about that and you should take good care.
anyway, my regular period usually takes 33 or 38 days. therefore, i thought i will not have m (if my FET fail) until i stop progesterone, even more than 14 days after ovalution.
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cutecutetown
It's really hard to say when miss M will come; some jm's have it return very soon, some take longer. I can only say that it will eventually come if bingo does not occur.
發表於 11-5-23 13:43
my endometrium is almost 19mm thck today already, and dr said it's too thick for ET.... besides, he said the ultrasound scan of the endometrium is kinda peculiar, though i can't fully understand... he said normally the endometrium under U/S should be black in color, but in my scan, it's rather white... together with the bleeding, dr suspected that i might have polyps inside. he suggested i may do 宮腔鏡 for checkup and remove them if there's any... i did such surgery last April and no abnormality found at that time.... i dunno if there are outgrowths over the past 12 months though...
and there are 8 visible follicles on each side today, average sizes ranges from 12-17mm... now we plan egg retreival this thursday, and dr predicted that there might be 13 follicles of acceptable size by then... however, in today's U/S, even the left ovary (while fibriod next to right ovary) was pushed further away and behind the uterus... so dr said there's technical difficulties in retreiving eggs from both sides now... so i might get less eggs than expected....
the hormone levels today are 2.7 and 14xxx...
so what i can do now is wait for thur and hope the egg retreival can be successful and smooth... yet we still need to decide what to do with the endometricum thickness and the need and options to do further checkup on polyps... i'm wondering is it wothwhile for me to pay for detailed medical report from HA? puzzled....
I wanna ask how do I know whether I have OHSS coz my tummy is really bloated.... I have told the nurse after 4 days ET and they did blood test for P4. I also told them today that my tummy is very bloated (people though I am 3 or 4 months preg) and sometimes I need to breath from my mouth but they still said I am OK.... What should I do?
This is all very weird and beyond my comprehension. While I don't have the medical training to give you much insight about your endometrial lining or intrauterine condition, I am again upset by the medical management given to you. But anyhow, there is no point to get you angry and disappointed with your doctor. Let's see what can be done to get the most out of the money you spent so far.
1. Are you sure you had 宮腔鏡 (hysteroscopy) before? Or was it laparoscopy in which your peritoneal cavity was being looked at, i.e. checking your ovaries, tubes, and any possible adhesion inside your belly? I think the HA doesn't charge too much for getting a detailed medical report. It may be worthwhile to get if it can save you from having another surgery.
2. Your ovaries are responding well, based on both U/S and your hormones. I really hope your doctor can manage to retrieve most of those eggs for you.
Are you due for your bingo check yet? How many eggs were retrieved, knew your hormones at that time?
I really can't tell or confirm if you have OHSS; and when you have the more severe form, you won't fit into your regular jeans/pants/trousers you normally wear. I also remember that you had quite a bad diarrhea a few days after your ET, could this now be again another episode of tummy sickness?
Did you actually visit your doctor's clinic this morning to get checked? Ultrasound, or physical examination especially around your belly? If all these were done, you should be ok. If all were just talking over the phone, I suggest you go into your doctor's clinic to get a proper checkup.
If you feel really really sick, go to an emergency room. Please 報平安when you can, thanks! Wish you well.
cutecutetown
My embroyos didn't implant in the end. I am losing hope in IVF (which is sort of my last resort) yet I can't and don't want to give up. Both my doctor and chinese doctor said that I have a good chance. My embroyos are of decent quality (ddespite the number), uterus lining is fine (range from 11 - 12 mm), normal uterine cavity with a smooth outer contour. From my chinese doctor's angle, my blood circulation is good and my uterus is warm.
But since both my transfers my embroyos didn't implant. I can't figure out what happened in this "blackbox". Everything else is more or less under control and known. I know I have approximate 6-7 follicles everytime. Out of the mature ones, usually all fertlised fine. Then it is always when the embroyos are transferred back into my uterus, it disappeared into my "universe".
I've thought about whether my uterus can't carry a baby. But this does not seem to make sense in view of my above desciption.
It's a pity that I can't get pregnant. My chinese doctor said that I have a good health from my "pulse", my organs are all functioning. I personally feel that my health is good - seldom get sick. Even if I do, I recover shorter with 1 or 2 dose of medication. It's really pity that I can't get pregnant. My IVF doctor said my case is positive from scientific point of view.
1. Would my blocked fallopian tubes be affecting the implantation? I have no hydrosalpinx. My chinese doctors said if the fallopian tubes are blocked, it does not have enough "blood air" flow into the uterus, thus affect implantation. How true is this?
2. Is implantation more a "luck" factor? my gut feeling is no. Many people implant fine, the success rate seems higher than a random luck factor.
3. I am losing confidence in IVF, even though everything is fine, why doesn't it implant in the end?
4. I want to continue with IVF....as I don't want to lose chance. I want to bear a baby by 33. my biological clock is ticking. I have started late given I got married at 28, I left this pregnancy aside thinking it will hit as long as we want to. I want to catch up with time now.
5. I can consider surgery to unblock tubes, but whether i will get pregnant is another mystery. IVF to me is more straight forward and to-the-point of getting pregnant. But I will still arrange for unblocking tubes, so as to give me hope in conceiving naturally in the future. Losing hope in life means losing everything.
just wondering what is the normal level of Beta HCG after 14 days of ET? if just 14 days of ET, can the home pregnancy kit (using urine ones) can be used to test instead of blood test?
i noted from this post that the no. of weeks count from the last M day. is it because the last M day is the first day for the new follicles to grow, so it count from that date.
by the way, i just want to share with other jm that i also have PCOS and my responses to Gonal-F is quite serious. therefore, my doctor decided not to do ET in that ivf cycle and therefore give me ovualtion injection (not the normal one, HCG) which will not trigger OOHS. therefore, i didnt feel any bad feeling after egg collection and i need to rest for a cycle before going for FET/
i found my discharge summary issued by PYNEH ... the procedures i went through last April include 1. diagnostic laparoscopy; 2. hydrotubation; 3. hysteroscopic biopsy of endometirum. And the result is: 1. uterine fiborid intramural, single; uterine size 6 gestation weeks; 2. unexplained infertility in femaile.
i suppose hysteroscopic biopsy is equal to hysteroscopy? i think they won't just take out the issue without examining if there are any polyps, right?!
since my hubby is away for a work trip, i did my injection by myself today!! i think i'm really brave!! will do the injection again tonight by myself, coz hubby can only come back at midnight...
can just keep my finger crossed for the egg retreival to be smooth and safe now. and thanks again for your support and information!!
1. IVF was originally "designed" to treat infertiile women with blocked fallopian tubes; it was much later that its coverage expanded to help other couples with other infertility reasons. So, you judge if what your chinese doctors said is true or not.
2. While "luck" may play a role, you need an embryo with implantation potential (i.e. developmentally competent). This is still something we can't "measure" or predict with 100% certainty.
3. I can't be sure either, but I believe the key is held by your embryos, given all your other conditions look favorable.
4. Sometimes, right thing will come at a right time. Try not to be too 執著.
5. Be hopeful. To you, I think it's just a matter of time.
There is no such thing as a "normal" level of bHCG 14 days after ET; but in those ET or FET where you are NOT given HCG injection(s) as part of the luteal phase support medication, about 2 weeks after your ET day you can check bingo, and a home pregnancy kit (the urine type) is usually good enough to tell you a YES or NO answer.
The no. of weeks of gestation counts the first M day as day 1; this is the traditional way of counting in natural conception, and the same principle applies to ivf pregnancies as well.
I am not very clear about your ovulation injection being not the normal one, HCG. What is it, do you know the name? Without knowing the name, I suspect it may still be HCG. Was your cycle done outside of Hong Kong? Just curious.
I am not sure if hysteroscopic biopsy = hysteroscopy. Now that you found the report, you can easily ask your doctor about it.
Yes, you are very brave; I have to give you 2 thumbs up!! Those jm's who can "easily" inject their own medication really amaze me; I mean, it involves holding that needle pen, pinching your own belly skin, and jabbing yourself and pushing in the medicine. I can't see how I can do it myself. And please give you beloved half a 2-thumbs-up as well, because it must also be a lot of emotional struggles in order to jab that so-called pen into your belly everyday for ~10 days. I am sure not many men out there who will say yes to this without hesitation.
Add oil,
cutecutetown
點評
糟糟豬
he is reluctant in fact, but no method la.. but i thank him very much too!
發表於 11-5-24 17:03
Is there any problem with fast-developing embroyos? My four day-3 embroyos are as follows:-
Two are cell-9 at grade A- and B+ respectively. Not cell-8 from my understanding. Both are transferred to me.
Two are cell-12 and cell-13 at grade A- and B respectively. This will be my for my FET.
My embroyos seem to be developing faster than normal. Is there any concern to it? I am an impatient person, maybe the embroyos resemble my personality.
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cutecutetown
Ha ha, maybe, their speed of growth may be "inherited" from mom :)
發表於 11-5-24 23:06
cutecutetown
They are not "abnormally" fast. I won't be too worried, not all embryos will be 8-cell on D3. On average, they range from 6- to 12-cell; so, even your 13-cell should be ok.
發表於 11-5-24 23:05
I got a similar question as PWYO7657. I had my FET last Sat and I transferred 3 day 3 embryos (7 and 8 cells in grade 2 and grade 2-). For luteal phase support, I am having daily injection of progesterone oil in shot and vagainal inserts 2 capsules X 2 times daily. Today I came back for blood test of E2 and P4 and like PWYO7657, I was told that my P4 was low (19 ng). For your information, my P4 was over 100 for the fresh cycle last month.
Since i heard that implantation normally occurred on day 5 - 7 (which was somtime from Monday to today), does my low P4 indicate that embryos have not implanted? Or there is no correlation like this?
I saw your previous answer and my P4 level is actually within the normal range if i was not given progesterone shots and that you explained these shots are likely to be reluctant given vaginal inserts are also given. So is that mean i should not be worried about my P4? Sorry that if i am repeating the questions but i just want to double confirm as the tone of the nurse made me very worried.
I asked my nurse whether my low P4 indicates that my chance is low. But she just looked very annoyed and told me what i can do if she told me my chance is low. She told me that i have gone through so much and I need to continue with what they tell me to do even though my chance is limit. The way she sounded made me felt i should not have hope for this cycle. Is that right?
點評
PWYO7657
actually after my low progesterone result, my doctor gave me HCG injection which i thought it's used to supplement this low result. any such injection for u?
發表於 11-5-25 17:36
Hi Cutecutetown
The 2WW is almost over and I'll have my blood test tmr morning. But it's not looking good as I started to have spotting last mid-night. During daytime I have had some more brown / red discharge coming out. I feel like Ms M is coming......
Of course I feel a bit disappointed.. My hubby told me to take it easy and see what happens after blood test. But i know the chance is slim now...
Thanks for your help and support. Maybe i'll take some rest and see how I can deal with the egg quality problem
Sorry don't know why i am not able to use 點評 function to reply. Yes, i was given HCG injection and was always asked to increase vaginal inserts to 3 times daily.
P4 level is not an indicator of embryo implantation. P4 is used to support the endometrium for a competent embryo to implant.
Yes and no to your worry about the low P4 level. Yes is because just like PWYO7657, I suspect that either you may not be injecting into the muscles, or your body perhaps quickly clears the hormone from your bloodstream; while we probably can't figure out a reason, now the "no" to your worry is that your vaginal progesterone is increased, which hopefully compensates the situation. The HCG shot also helps the endometrium.
So, don't be scared by the nurse's tone; simply make sure you have the 3 daily vaginal inserts and you will be fine. And if you still need to do the progesterone shot, continue doing it and pay attention the needle really has to go deep (well, I don't really help here because I am not a nurse and don't know how to do intramuscular shots). The way you described your nurse made me think that she probably had a rough day; don't get affected by her mood :)
By the way, are you using your own natural cycle? What's the quality of your embryos?
cutecutetown
I agree with your hubby to take it easy and see what the blood test will tell.
While trying not to give you false hope, I do have patients who told us they had miss M returned (they even said it's full M, not spotting), and we all assumed they failed; then, 2 weeks later, while in planning FET or simple counselling, we actually figured they had their bingo all along. My advice is, still go for your blood test tmr because the test is quantitative and tells more objectively what is going on.
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