cutecutetown, I'm new here. I had one IVF earlier in March. It resulted in a chemical pregancy. I have two more day-2 embryos and plan to have FET this month, but I have a diarrhea from day 3 to day 5. would it affect my FET?
Besides, may I know would low blood pressure affect the success rate of IVF/FET? My blood pressure is about 9x/7x, which doctor used to say it is ok but chinese doctor would say it is too low
thanks cutecutetown!
i called the clinic and they explained that they did icsi for us mainly coz my hubby's semen analysis showed that morphology was a bit low (4%, whille they used 14% as cut-off reference). So they decided to do ICSI to maximize the success rate....
besides, the total motility rate was a bit lower than in the past, 2x% rapid + 4X% slow, which was the reversed as we did IUI in the past... dunno if it's coz the number of days for keeping no sex was not long enough or he might be too anxious?!...
i dunno, my feelings are a bit complicated.. i know my result is good.. but perhaps i haven't really prepared for ICSI... so i felt not as happy as i should be.... i shalll try to adjust my mind anyway...
i just did ET on Sat. but i wonder why embryos can be 7 and 8 cells. is it not good if the embryo with odd cell split?
Before ET, my breast was tender. but now it resumes normal. does it mean i fail again?
Do you mean your diarrhea happened in your last cycle in which the chemical pregnancy occurred? The diarrhea was probably not the cause of chemical pregnancy; rather, it's probably an incompetent embryo. Not too long ago a few jm's here also asked about the same; one of them had a few days of serious diarrhea after ET and also before her bingo check, but... she bingo alright!
It also happened that I reconfirmed with 2 doctors from 2 different clinics that diarrhea is quite common in fresh ET because after retrieval, there would be some blood (very minor) inside your peritoneum (tummy cavity) which irritates your bowel. This in turn causes more bowel movement, causing diarrhea in some women. Besides, I am sure jm's are also anxious after ET, which may also increase bowel movement. As long as you watch your diet and don't eat anything contaminated, ivf doctors and I will all tell you not to worry.
As for FET, if your diarrhea happens way before FET, it shouldn't affect outcome either. Afterall, your digestive tract is separate from the reproductive tract. If your diarrhea does not stop after 2-3 days, I am more worried for your general well-being rather than the FET.
I have never heard or seen low blood pressure causing implantation failure. If you choose to do ivf with your ivf doctor, you should trust what he/she told you; it doesn't matter what other doctors of other fields said.
Best wishes,
cutecutetown
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a_mom
But thanks very much for explaining in detail... hehe. i will go ahead then
發表於 11-5-30 20:19
a_mom
Sorry for not making myself clear enough. I mean I'll have FET this cycle, but just had diarrhea.
發表於 11-5-30 20:18
Are you worried about ICSI causing abnormal baby?? I think the worry is unnecessary because even though your hubby's sperm is in the ICSI category, the parameters are still very good as compared to some others. Although I can't totally exclude the possibility of an abnormal bb, its occurrence would almost equal to that in natural conception, i.e. very very low. Don't forget that when you get pregnant, you will have 9-10 months of gestation, and if anything is suspected, your doctor would refer you to check-ups and so on. Same kind of management as in natural pregnancy.
And with my post #1100, I hope you read till the end that there are variations in sperm quality in different sperm samples given at different times. Your hubby's sperm might still be alright doing ivf, but in the lab, we couldn't afford to risk your eggs not getting fertilized after ivf, so we did ICSI instead. It is a day-to-day routine to make this ivf-or-icsi decision; sometimes we could be wrong in doing ivf when sperm doesn't show any tell-tale sign and we need to icsi the next day due to no/low fertilization, which would probably be more emotionally traumatic to the patients. Don't think as if you are an odd and rare case; believe it or not, some patients ask for ICSI even their sperm quality is great.
As for the period of abstinence (no. of days for keeping no ejaculation), it should NOT be kept too long. The recommendation is to abstain 2-7 days before giving a sperm sample. Too long is not good; and a man can always masturbate to get rid of "old sperm".
Take it easy, you have some good embryos and that's the most important. cutecutetown
It is very common for human embryos to have odd number of cells because not all cells divide at the same time. e.g. let's say you have 2 cells to start with and one is dividing first but the other is waiting, then after this division you will have 3 cells.
It's way too soon to say you have failed; practically, there is no sign to tell unless your period returns.
thanks so much, cutecutetown. it's my second IVF already. Last time, i have 5 embryo with good quality, but it's failed. This time, i have 8 embryo out of 23 eggs, but it comes with poorer quality. So i'm not confident. anyway i tried to tell myself not to think about it.
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cutecutetown
7-cell and 8-cell embryos, at least in my lab setting, are good embryos. Do not give up hope :)
發表於 11-5-31 14:10
cutecutetown
how far apart were your 2 ivf cycles?
發表於 11-5-31 14:09
cutecutetown
Very discrepant in number; do you have PCOS (polycystic ovary syndrome)?
發表於 11-5-31 14:09
thanks cutecutetown,
i did read through the end of your last post. thanks a lot for the information! well, i can't clearly tell what i'm concerned about... i'm not really worried about the health of baby made through ICSI, i know that data showed similiar risk... perhaps coz in my mind ICSI is a more invasive procedure, and to me that means more "unnatural"... i know for us the infertile, things can't really be "natural", and ivf itself is invasive already... i really consider a long long time before i can accept ivf... so perhaps i just need more time to accept icsi....
we used to keep 5 days of abstinence in our IUI cycles, but this time, the nurse told us to "clear" the old sperm on the night i injected Decapeptyl... so it's like thirty sth hours before IVF only... it makes me related to the lowered motility rate of the sperms this time, as compared to the past... i know it may not be valid.. and it's not impt now, coz anyway the embryos are ok :)
but i have new question again.. i tried to chart my body temp again just to predict when i may have menses... after two days of high temp, it began to drop yesterday, and i have mild bleeding this morning.... i dunno if it's M or not... i will observe today and see if it persists... but isn't it jsut too short? it's just day 20, and 5 days after ER....
Simply forget about charting your body temperature. This is a stimulated cycle, not a natural cycle; all hormone levels are not physiological and basal body temperature is not going to tell much. In those women who will have ET in this same cycle, they will have hormone supplementation (luteal phase support medication) which helps to "re-create" a similar environment to allow a pregnancy event. In your case when you don't plan to have an ET, no supplementation is given and therefore the cycle may be shortened. And if you have already had some mild bleeding, your M may come soon; in such case, it is still normal.
I agree with you that if it takes you some time to accept ivf, it will take you some time to accept icsi. To me, because both are my routine life, they are almost "natural" to me. Remember that whether the fertilization happens inside your body (in vivo) or outside your body (in vitro), nothing genetic is being changed. Some people think of the ivf process somewhat like genetic engineering, but in reality, unlike genetic engineering in the food industry, ivf/icsi does no manipulation on the genetic level. The technology (used in ivf) is far from being able to play God. We simply put sperm and egg together, without being able to guarantee "one embryo = one baby".
A quick note with abstinence, what I found over the years is that longer abstinence may increase the sperm number but usually decrease sperm motility (or, shorter abstinence results in slightly fewer sperm but a little better motility); morphology doesn't change much due to abstinence.
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Thanks cutecutetown!
If u don't mind, would u share how u pick up the sperm for injection? Is it by how it looks or swims, or just randomly?
Besides, I read in the forum from some jm talking about natural cycle FET vs another (I guess it's using drug), can u explain what are the differences and what r the considerations behind?
Which sperm to pick is a relatively subjective judgement of the person performing the injection; but at least I can tell you how I do it. Before anything, you may need to know that the sperm we use for ICSI has undergone some preparation and we rarely work with the original sperm sample (i.e. sperm in semen). However, in cases where sperm is very scarce, we may spend hours searching in the unprepared semen sample. (A few times I spent 4 hours in finding ~10 "usable" sperm.)
Generally, I always look at motility first, and the fastest sperm with forward progression is my first choice. We have viscous solutions to slow down sperm movement, in case you wonder how we catch a sperm. We also immobilize the sperm in this viscous solution (the sperm can't be swimming around inside the egg, right!). After stopping sperm movement, I examine its morphology; if it looks good, then it will be injected into one egg, if not, I repeat the above process until I find a sperm that I am satisfied with.
Of course there are times when there is no forward-swimming sperm, or all sperm has sluggish movement, or even no motile sperm. Then we have ways to tell if the sperm is truly dead, or simply alive but not moving. I will not go into how we do it here, but the bottom line is to deliver a living sperm into an egg. Only very very rarely there is no sperm with normal morphology despite they still swim ok. In such case, all I can do is to find a sperm with "borderline-normal" morphology.
The physiological milieu of natural cycle FET vs FET by hormonal replacement is similar. An easy example is that if a woman has normal ovulation and regular menstrual cycles, then a natural cycle FET is easy and well-timed; but in women who have irregular cycles, ovulation is difficult to time and hormonal replacement comes in to create the cyclicity. As natural as it can be, natural cycle FET does not require medication. Hormonal replacement requires some, but in a much smaller quantity as compared to a full IVF cycle. In HK, we tend to use natural-cycle FETs whenever possible; a lot of western IVF clinics nearly do all FETs by hormonal replacement because of easier time-management (for the clinics/doctors, not necessarily for the patients). Success rates between the 2 methods are also similar.
For the use of supporting medication (if it will be needed), you may read my previous posts #998, #1002, #1050, #1083 and see if you can find some answers there.
Looks like you will have some "homework" to do now. Let me know if you'll have further questions :)
cutecutetown
i did my 'homework' la~~ thanks a lot! learn a lot from you indeed...
so i understand that the coming month is not only for my body to take a rest, but also to observe if i can ovulate as normal, so as to decide whether i should have a natural cycle FET or with hormonal replacement, right?
also thanks a lot for your detailed description of the ICSI procedure. i think knowing more can facilitate my "acceptance" process to certain extent. thank you very much!
It's me again. Does 水胞 in the uterus (a side-effect from IVF injection) affect implanation? It is not water cysts. It is "sui pok" which will go away by itself later.
I had "sui pok" in my last cycle. I wonder if this affects my implantation.
Did your doctor tell you that these "sui pok" are in the uterus? Was there just one or multiple? Are you sure it/they were in your uterus?? I just don't see its/their presence in uterus on ultrasound of women having ET or FET.
On the other hand, on the day of fresh ET, we often see the ovaries still with "sui pok"-looking structures. Those are the empty follicles in the ovaries, with eggs already removed, and I suspect that is the "side effect" of ivf. If this is the "sui pok" you mentioned, then they won't affect implantation.
cutecutetown
點評
mother2be
I checked with the doctor. The "sui pok" is in the ovary not in the uterus. A side effect of IVF.
發表於 11-6-8 09:48
I am preparing to do FET this cycle. I am using natural cycle. Today is day 11, my uterus lining was only 6.2mm and my follicle size is 13mm. I took some chinese medicine this month in aim to help with my uterus. It does not seem to help. =(
Doctor prescribed some estrofem tablets (one daily starting today) and 2 breville injections (to keep my eggs in good quality so as to stimulate my body to ejaculate estrogen per doctor). How do these two items help with increasing uterus lining?
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