想生BB 今日: 6 | 主題: 109608

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1442^#

發表於 12-3-14 22:58 |只看該作者

回覆 cutecutetown 的帖子

Hi Cutecutetown,

My HCG reading is 0.6.....
Well i know I've failed, but would it be possible that my embryo is just a bit too slow? Since it was a 2-cell when it gets implanted.

I know the average successful rate is around 40%... but I just turned 32, low FSH 3.x, low LH 2.x, grade 1 cell and I've done nothing much for 2 weeks so I thought i could be the lucky one.
Well I have 2 big ovary cysts but my Dr. said it has no effects to ivf.

The 2 failure reasons I could think of was i was over-heated myself. I thought i gotta keep warm and thus.....sweated a lot more than usual. Could this be the reason?
Or E2 was too high when the ET was done? It was 13,000pmol/L

Should I do another HCG test or just forget it?

點評

cutecutetown No one can ever figure the reason for failing, but in most cases, it is the embryos not competent. 發表於 12-3-15 08:37

cutecutetown Only if miss M won't return by next Monday, then you may do another HCG. 發表於 12-3-15 08:36

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VIVIANTAA

積分: 1836

1443^#

發表於 12-3-20 18:18 |只看該作者

cutecutetown,

你好. 我需要回台灣放D5雪胎, D1是3月3日. D12開始自己用排卵測試, 一直都是negative, 但醫生叫我3/18去驗血. E2=330 P4=2.5 , 醫生說還未排卵. 明天要再去驗血check E2 及 P4. 我想問其實E2=330 P4=2.5是否快要排卵, 還是要再驗血才知道大約何時. 因我好心急想知(要訂機票又要請假),成個人變得好緊張. 可否解釋一下E2 及P4 會如何轉變. 真的謝謝你.

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積分: 9498

1444^#

發表於 12-3-21 22:35 |只看該作者

回覆 VIVIANTAA 的帖子

Hello VIVIANTAA,

I probably didn't answer you soon enough. I hope you are coping with your anxiety ok.

Did your doctor ask you to 自己用排卵測試? I think you are using your own natural cycle for D5雪胎, correct? Assuming you have very regular cycles, what is the average length, 30 days?

The first check on E2, P4 won't tell much, especially when they are low. I think your doctor is looking for a gradual rise of E2 with a relatively stable P4. When E2 starts to increase, he may soon check LH as well, which is the hormone that triggers ovulation. Given your embryos are day-5 embryos, you will have about 6-7 days before the actual embryo transfer from the time of ovulation. However, we can never really pin-point the exact day of your LH surge (ovulation); usually we estimate it based on those blood test results. But still, with good blood monitoring, you will often have ~4-5 days notice in advance. I hope that will help you to plan buying the air ticket.

Just in case you worry about the numbers of E2 or P4 levels... I suspect your E2 (330) is beginning to rise, P4 is also fine. The numbers alone can't predict when you will ovulate, it is the overall trends that allow us to estimate when you ovulate.

Try to relax, ticket to Taiwan should be easy to book. (are you in HK?)
cutecutetown

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VIVIANTAA

積分: 1836

1445^#

發表於 12-3-22 00:18 |只看該作者

Cutecutetown

謝谢你的回覆，你的解释真是令人明白及安心。今天去了跑步，心情平伏下來。我是在香港的，醫生叫我自己用排卵測試，可能太緊張一見測試有兩條線（negative 的兩條線）就去問，所以後來又叫我去驗血，但一般驗排卵是驗LH，所以我不太明白。對，我是用自然週期。但每晚在食parlodel (㧕乳分泌），雖然醫生確診，我的乳分泌不是高。他說這薬對整體都好。我的週期不定，34-39日，但之前有一個月食過這薬，就30日來經。

不好意思，我還有問題。
1） 3月21日。E2=407 P4<1 我只知道E2增加，那是代表卵泡長大。但那P4指數又代表什麼。今天跌至＜1。
2）我想問D5雪胎，有多少機會成功溶雪。
3）放雪胎的成功機會是否比較底

謝謝你的幫忙。

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積分: 9498

1446^#

發表於 12-3-22 14:15 |只看該作者

回覆 VIVIANTAA 的帖子

Dear VIVIANTAA,

BabyKingdom website is very strange lately, so I stop using its phone Apps and go back to a regular desktop. However, I cannot write in Chinese with my desktop; I hope you read my message ok.

To answer your questions:
1) As mentioned previously, P4 will stay "relatively stable". Even it drops from 2.5 to 1, this does not mean anything. When P4 starts to rise (say going >10), you should have ovulated.
2) This depends on your embryo vulnerability to freeze-thaw, and sometimes on the freezing method used. Really hard to predict survival after thawing.
In my lab, D5 blastocysts have good survival >80%.
3) Again, if the embryos/blastocysts are thawed ok, their success rate is just as good as when they were fresh.

cutecutetown

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VIVIANTAA

積分: 1836

1447^#

發表於 12-3-22 16:57 |只看該作者

cutecutetown

真的謝謝你這麼快的回覆, 英文回答是沒有問題. 你回覆令明白了很多. 可能台灣覺得不需要解釋那些指數, 今天只回答我還未排卵. 我需要繼續用排卵測試到positive.

其實我明白只有一個雪胎, 機會係好細. 沒有期望好大, 但由驗排卵開始, 就緊張起來.

點評

cutecutetown No worry, it will come, be it 1 day or 1 week. Relax and enjoy this weekend in HK. 發表於 12-3-22 17:13

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kakakaju

積分: 1609

1448^#

發表於 12-3-22 16:58 |只看該作者

Hi cutecutetown,

I am 39 yo failed 3 natural IUI and the 4th one IUI I also failed last week. This 4th one was done through a whole series of injection. Honestly I did all necessary body check inside out and my husband is also in perfect condition. However, doctor is unable to tell while I failed the 4 times IUI, the only possible reason was my age, though I have eggs quantity but quality might not be as good that's my rare guess.

I am undergoing now IVF cycle, started my injections on Saturday and I should be ready to get my eggs out next Wednesday or Thursday. My process is via private lab and clinic that's why it can be done so soon. Shortly after I have decided going through IVF, my emotion dropped to the bottom as I have anxiety and depression which my doctor know and I have been under psychiatrist supervision with medicine since a year ago. I am not sure what is the best thing I can do to tune myself up in a better mood so as to undergo IVF. I have my 2nd checkup yesterday and doctor said my egg quantity is around 9-10 eggs and I have the average 30 years old women eggs quantity which the doctor feel blessed. I also have a minor cyst in my uterus which doctor said he will decide when he put the embryo if the cyst did grow he will refrain from putting the embryo till next cycle.

I know it's hard to ask you how I can tune up myself in a better mood and how do you see my condition per what doctor said have the 30 year old average egg quantity?

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kakakaju

積分: 1609

1449^#

發表於 12-3-22 17:32 |只看該作者

Hi cutecutetown I fogot to mention that I have gone back to my psychiatrist yesterday and she has mentally and physically told me the hardship I will have to face. I just wanted to well prepare myself given my emotion is so unsteady for the past few days. Plus doing IVF in private practice is causing me 80-100k and I don't want to throw money into the sea, I need to have the courage and the faith to look for the success. I'd like to ask you how I can prepare myself?

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分分

積分: 877

1450^#

發表於 12-3-22 22:48 |只看該作者

回覆 cutecutetown 的帖子

第1次IVF,當時醫生只照倒3粒, 醫生話卵生長很慢, 等唔倒未熟的, 怕排左出來, 抽唔倒, 所以3粒都照抽, 結果抽卵日上午抽左10粒, 3大6小, 1粒未熟, 第2日通知我9粒都可分裂, 第3日先放3粒, 雪6粒, 我無問放大定細, 結果FAIL左, 我想問細的是否比較難著床成孕?

有時見JM 話胚胎是DAY 3 - DAY 5, 醫生都無問要唔要等到分裂到DAY 5才放, 其實分裂大一點才放入體內, 會不會比較易著床成孕?

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zarara188

子爵府

積分: 13137

1451^#

發表於 12-3-23 17:05 |只看該作者

本帖最後由 zarara188 於 12-3-24 14:58 編輯

回覆 cutecutetown 的帖子

Hi Cutecutetown,

I have been watching this post for a few months.
You are really a very generous and kind person who can share your experience with us and comfort us.
Thanks alot!

Let me tell you about my background.

as u know, women have PCOS normally do not have good quality of eggs.
These 14 embryos will be frozen.
I asked my doc if i need to do another blood test before FET, she said no.

As I heard from the other jm here, they need to check LH/ E2 before FET.
Why i don't need to do so?

She said I just need to call the hospital when m return next cycle, and then will do the u/s
and see if there's still 積水 in my tummy, (bcoz she found some 積水. bcoz of ohss?)
if there is no more 積水, then she 'll give me about 14 days of hornmones medicine, (pills)
and no more injection, no more blood test is required.

I am just wondering why I am differ from the others?

WHy some jm need to wait for their FET until they ovulate?
HOw do i know whether i have ovulation or not next month? (bcoz i don't ovulate every month)

another problem is, i feel quite painful(tummy) when i walk. even worse, i coudn't breathe well
these 2 days, i find it quite hard to breathe especially
when i lie down on the bed, it seems that there's something 擲住心口.

is that also caused by OHSS?

sorry for so many ???????
thanks a lot!!

I just want to have healthy babies!

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積分: 9498

1452^#

發表於 12-3-23 21:44 |只看該作者

回覆 kakakaju 的帖子

Hello kakakaju,

I feel for you, and indeed, many couples who go through ivf, regardless of previous IUI attempts, do not succeed the 1st time coming through. The exact reasons for failing are probably impossible to fully define, keeping in mind that even women with normal fertility only have ~20% chance of conception each cycle. While I don't want to put you in despair, I will need to warn you about the negatives so that you are prepared and well aware that you are not at fault and no women should ever blame themselves for not succeeding in an ivf cycle, or fet, or iui cycle.

I am also proud of you that you are seeing a psychiatrist for help. It is stressful for anyone to go through ivf, with all the unknowns and also the emotional "knowns" that you need extra help in having babies and many do race against time; on top of all these, ivf does create known and unknown financial pressure as well. For you in particular, the hormone injections may further affect your mood, making you feel very low all the time. For mood issues, I will suggest you seek your psychiatrist since he/she has already known what you are going through and hopefully you should make one or two extra visits to him/her if appointment booking allows so. Assuming you will finish this round of injections, proceed with egg retrieval, have 2 embryos for transfer, there will still be a 2-week waiting before checking pregnancy outcome. The actual physical procedures, timely & daily medication, and the waiting are all demanding on you. So, if you can book a few sessions with your psychiatrist, that will be good. On your day-to-day activities, try to be active and busy yourself. By "busy", I mean, just do something: watch movies, tv series, meet with friends, take a walk in a park, do a bit of exercising, cook healthy meals for yourself; anything that can distract you from thinking too much.

A last note about your doctor's comment -having a 30-yr-old egg quantity. Just a very general description, statistically, a 30-yr-old woman is young and tends to have more eggs. You should take it as a good sign that you have comparatively more eggs than many others who are at your age.

cutecutetown

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1453^#

發表於 12-3-23 22:39 |只看該作者

回覆分分的帖子

Hello 分分,

The follicle size no longer matters as long as the eggs retrieved were mature. When eggs are mature, the majority of them are fertilizable; in your case, 9 of them were mature, all fertilized and became embryos.

We won't really trace back to which egg comes from which follicle, although as an overall picture, mature/immature eggs correlate with sizes of the numerous follicles. It is a good question whether mature eggs from "small" follicles have lower implantation potential; my guess is NO, unless the egg is immature on the day of retrieval or the egg is genetically abnormal. As "egg reserve" was born with a woman, the older she is, the longer those eggs have been around exposing to different environmental factors. Therefore, older women tend to have a bigger proportion of eggs being genetically abnormal / not able to produce a heathy baby.

It makes sense that if we let an embryo grow to day3 (an embryo of 6-8 cells) or day5 (a blastocyst), we see its potential so that it has a better chance to implant. But in many cases, we need to balance the possibility that perhaps no embryo will reach its expected stage and then a woman will not have an embryo transfer. And transferring a day5 blastocyst gives a better chance than transferring a day2 or day3 embryo; however, it still does not guarantee success. So, many doctors rather give you D2 or D3 ET.

Another way of explaining it is that growing embryos longer will not boost an embryo to implant; instead, it helps to pick out the good ones and de-select the bad ones. Let me give an example to better understand the scenario. e.g. I have 6 embryos, #1,#2,#3.....#6 and only #5 and #6 can give babies. On D2, all of them are growing and all are 4-cell. If this is the day of ET, I will probably have #1 &#2 transferred and the other 4 frozen. This will make me fail, come back for a FET, transfer #3 & #4, face another failure. When starting to doubt myself, do another FET, maybe doing something extra such as having aculpuncture or taking some Chinese herbs, transfer #5 &#6, bingo. Having twins at an older age.
If we grow those embryos to D3, perhaps only #3 to #6 grow to 8-cell. Similarly, #3#4 for transfer with #5#6 frozen. Not too bad, twin birth after my first FET. If we grow those embryos to D5, only #5 & #6 become blastocysts; so ET #5 and freeze #6, or in some cases, ET both. Bingo.

You can see that if there is at least one embryo being a baby-to-be, it is a matter of time to come to it. However, there may be some baby-to-be embryos, or just one, or none. So, we all try to balance time versus what is the best for a particular woman. While twins are widely accepted, carrying twin pregnancy poses much higher risks for both the mother and the babies. We should all aim at having a healthy singleton birth.

cutecutetown

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分分

積分: 877

1454^#

發表於 12-3-23 23:12 |只看該作者

回覆 cutecutetown 的帖子

Hi Cutecutetown,

thank you for clear explanation. really nice!

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積分: 9498

1455^#

發表於 12-3-23 23:17 |只看該作者

回覆 zarara188 的帖子

Hello zarara188,

Don't worry, you are only giving me 2 questions.

1. Are all the pain and discomfort caused by ohss?
Please forgive me that I am not a medical doctor; but I can say some are from the egg retrieval procedure and some may be a mild sign of ohss. The retrieval needle has at least poked your 2 ovaries 26 times to get those eggs, you will need some time to recover! In the next few days or so, if you continue to find it hard to breathe, or having an increased waist line, do not hesitate to call your doctor and seek some medical advice.

2. Why you don't need blood test before FET?
I think you do not ovulate regularly or having timely regular menstrual cycles due to PCOS. I am guessing your doctor will use an artificial cycle for your FET. Unlike a natural cycle, she gives you hormones to simulate a normal cycle; at certain time points during this artificial cycle, she may still need blood tests, but what she looks for is different than in a natural cycle-FET.

You are still somewhat far from your next FET. For now, focus on letting your body recover. Keep an eye for any ohss sign as mentioned above. Take care,
cutecutetown

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zarara188

子爵府

積分: 13137

1456^#

發表於 12-3-24 15:23 |只看該作者

本帖最後由 zarara188 於 12-3-27 19:50 編輯

cutecutetown 發表於 12-3-23 23:17
回覆 zarara188 的帖子

Hello zarara188,

Hi Cutecutetown,

Thanks for your reply.
I felt much better last night. hope will totally recover within these few days.

Do you think i can go jogging 1 week after my egg retrieval?
as i heard from many jm, doing sports is good for us.

would you suggest me to put 2 or 3 embryos?
as i am afriad of having miscarriage, just in case all 3 embryos are lucky enough
to 著床成功, i won't be so hurt even i lose one. Am i silly ?

May I ask about the probability of being bingo?
if 1 embryo is put in my uterus, the bingo rate is about 1/3.
if 2 embryos are put, the bingo rate is about 2/3.
if 3 embryos are put, the bingo rate will become 3/3. (almost 100%!!!)

Is my formula correct or not?

hehee.... thanks again for your professional opinion!

I just want to have healthy babies!

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積分: 9498

1457^#

發表於 12-3-24 21:24 |只看該作者

回覆：zarara188 的帖子

Dear zara188,
Jogging is a good way to exercise. As long as you 量力而為，mild exercises this week should be good for you. You may increase slowly the 'intensity' after 1 week. Moderation is the key

For your age, 1st-time ivf, good-quality embryos, I would suggest a max of 2 embryos back. Although you don't mind twins, twin pregnancy has its risks, & higher-order pregnancy is worse. No need to be so aggressive yet to put back 3.
Your formula is 太樂觀. Although it is possible all embryos are competent, we are not always that lucky. Read my message to 分分about 2 or 3 posts ago to see my example on 'baby-to-be' embryos. Generally speaking, if the jewel is there, it is there waiting for its chance to come. We need to balance time & risks.
存活率depends on embryo quality as well as the stage (D2,3,5) when they were frozen. On average, it's ~70-80% for good-quality embryos.

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kakakaju

積分: 1609

1458^#

發表於 12-3-26 11:33 |只看該作者

回覆 cutecutetown 的帖子

Thank you cutecute town for your long advice. I am trying to keep my mind stay neutral and also be calm to go through egg retrieval. Luckily my husband is very supportive and he and I know there's nothing guarantee especially woman at my age of 39 years old. What I'd hope and try to do is keep myself at ease and relax, its easy to say hard to do. I do know one jm from BK she encouraged me try to divert my attention and probably think less....cos I have gone thru IUI since the past 3 months, putting pressure on myself will create negative impact. I am well prepared for the worst to come, seeing psychiatrist is good but my psychiatrist can only verbally support me etc as she cannot guarantee anything still. I am already under anti-depressant so in a way my emotion is at times controllable. I guess the most difficult things to face sometimes is seeing your relative or friends being able to bingo via IVF and not me...this is also a tough time when you have a comparison or some kind of competition.

I also know that have quantity of eggs doesn't mean anything I know some doctors are able to tell patients on their success of IVF in terms of % but I'd rather not to put expectation on my own doctor. Evenso if I am told there's a 90% chance you still don't know if there are other factors that impact the growing of the embryo etc. Personally I do have a small cyst inside my uterus and my doctor said that shouldn't impact too much of IVF but he will monitor the size of my cyst when the input of the embryo happens, the worst scenario is to freeze the embryo for the next cycle.

Anyways I believe in "fate" the more you force the more difficult for the baby to come and it also impact mother to be. For the time being I will not think too much cos the more I think the more I look upto the internet I get more worried. Thanks again cutecute town!

點評

add oil! 發表於 12-3-26 16:42

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peteto

積分: 5287

BK Milk勳章

1459^#

發表於 12-3-26 13:47 |只看該作者

Hi Cutecutetown,

你好. 我在3月18日放胎,之後KEEP位塞藥..今日(應該DAY８）見到有小小紅色分泌＋Ｄ藥留番出來..是代表失敗

唔該

點評

cutecutetown Continue your vaginal support. It is still a little too early yet unless you have a flowing period. 發表於 12-3-26 16:47

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kululato