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發表於 12-5-22 19:58 |只看該作者

回覆：kakakaju 的帖子

Thanks, u will be the next!

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1643^#

發表於 12-5-22 22:30 |只看該作者

回覆 pigsmoomoo 的帖子

Hello pigsmoomoo,

It is too soon to try estimating when dr will do your egg collection. Once you are given and started nasal spray (day 21), you will continue until your period comes. Then your dr will decide when to start you on stimulation drugs; suppose you are on, your dr needs to see your ovarian response. In many, stimulation takes 8-12 days, but some may take a little longer.

通經丸is to induce menstruation. Day 1 of a menstrual cycle is the day when your period comes, with a red blood flow.

cutecutetown

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1644^#

發表於 12-5-22 22:44 |只看該作者

回覆 Racian 的帖子

Hello Racian,

1. It is generally good laboratory practice that we don't freeze anything that has no potential. In other words, when we freeze any embryo, we believe it has growth potential. I can't really tell you if your day5 embryos were actually day4 or day5, but I would choose to trust the lab's judgment as we see embryos under the microscope everyday. Medical doctors don't take care of embryos, they only see photos once in a while.

2. I would transfer the frozen embryos first; and if you don't get pregnant, then you may start a new cycle with this new doctor.

Good luck,
cutecutetown

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Racian

複式洋房

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1645^#

發表於 12-5-23 10:21 |只看該作者

回覆：cutecutetown 的帖子

Thanks a lot Cutecutedown ! What you said is so true and I really want to give my embryos a try !

I took a closer look at my report. May be because it is stated there that the embryos are morula and that's how the doctor concluded that they are not in good shape .... Anyway, I will start my natural FET cycle and hopefully there will be some good news ! Thanks Cutecutedown !

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發表於 12-5-23 10:38

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CoolMoMo

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1646^#

發表於 12-5-23 17:04 |只看該作者

hi cutecutetown,

我有一個6cm既子宮肌瘤生喺子宮後面:
1)想問下做ivf前係咪要割咗先呢??
2)你有冇見過有肌瘤做ivf可以成功呢??
3)如果割咗要幾耐至可以開始ivf呢??

thank you for your advice~~

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1647^#

發表於 12-5-23 22:28 |只看該作者

回覆 CoolMoMo 的帖子

Hello CoolMoMo,

我唔係婦科醫生,而且單憑知道你有子宮肌瘤,好難判斷你要否做ivf。

假若你的肌瘤只在外肌肉層,一般都唔影響胚胎著床及懷孕。你可先約見ivf醫生,做一個基本診斷,到時醫生就可評估各方因素,再同你解釋下一部你須要做的檢查或療程。

cutecutetown

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CoolMoMo 唔該晒你呀~~~~ 發表於 12-5-23 22:43

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1648^#

發表於 12-5-24 15:33 |只看該作者

Hi cutecutetown,

My last menstruation happened on the 16/4 (1st day) and my ovulation only starts on the 6/5 so I did my FET on the 12/5 per doc instruction and he was only able to put one blastocyst under 3BBB for me as he claimed putting more than one will put me at risk.

I went home start doing the injection (only 2) per instruction and also putting Crinone8% everyday. I was advice to check using home pregnancy kit on the 23/5 but I also try testing on the 21/5 onwards during the 21/5 and 22/5 I saw very faint line on the metholadum pregnancy kit. I was not excited cos I knew faint line didn't mean anything but luckily my period didn't come yesterday so I called clinic and they adviced me to go and do blood test. So I went to do blood test and the outcome is less than 1 honestly I don't know that means, but the nurse was not helpful to explain just say that means I am not pregnant. She then adviced me to stop Crinone8% so my period will come within a day or two. I stopped Crinone8% last night. Honestly this cycle I did my own homework during ovulation as well as FET...in previous cycles all the way through I have pre period system such as painful breast on the side and very very bloated tummy. Hence I have lost all these kind of feelings this cycle.....the most worrying part is I am 18 days past my ovulation which is not normal as my period cycle is very accurate.....longest was 32 days and shortest was like 28/29 days. I am NOT at all under stress as I predict this FET cycle I will fail so I was not putting hope.

Do you have experience that past IVF/FET can impact such a delay in period?

Thanks!

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1649^#

發表於 12-5-24 15:44 |只看該作者

回覆 Kittymoon 的帖子

no la kittymoon thank you but i think i will 'stop' here for a while...these five months is too stressful....i just did my FET on the 12/5...period hasn't come till now day 39 which is 18 days past my ovulation. when i did blood test yesterday the nurse said result less than 1 so no pregnant.

all i hope now is my period comes soon and everything for me is over. i am fine not to expect any more hope on IVF/FET as it's fate to have a baby! though i have still 2 frozen embryo left will leave it but congratulations again!

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1650^#

發表於 12-5-25 14:05 |只看該作者

回覆 kakakaju 的帖子

Dear kakakaju,

Your "delayed" period is probably due to a longer follicular phase (from your menstrual day1 to day of ovulation, 16/4-6/5, which is somewhat ~20days). Then you also had 2 injections as well as daily Crinone, both of which "tricked" your body thinking that you were pregnant. If your blood level of HCG as measured yesterday was <1, then you are not pregnant and your period should come back soon.

Some women experience delay in period, while some have earlier period after the immediate IVF/FET; but once your body comes back to its normal state (without any injection or vaginal support medication), your period will return to its regularity again.

cutecutetown

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1651^#

發表於 12-5-25 16:33 |只看該作者

回覆 cutecutetown 的帖子

Thanks cutecute town yes my period finally came back late yesterday afternoon. I wanted to ask your opinion since I have been with this doctor for 5 months since starting my IUI/IVF/FET, I count myself as still under the 1st IVF cycle as I failed this FET I am still left with 2 frozen embryo. I was wanting to change doctor and at the same time maybe transfer out my frozen embryos. Do you think this is a good move or you think I should stay with this doctor to do the remaining two transfer before moving out of them?

Honestly I am at the clinic where they have their own lab already...but I am not feeling happy or comfy with the failing rate of my current doctor without a susbtantial explanation apart from my age 39. If me or my husband have health issues then I might admit to its reality but the fact is we are both healthy. Does IVF/FET really depends on the expertise of the doctor on it's successful or more on the condition of the embryos? I did call the lab and they said it is possible to transfer out the embryo to another lab but they do not take the risk of the transportation process etc or any associated risk?

I was also adviced by another JM to ask for laser hatching technique whereby I am not even sure if my lab offers such an alternative to enhance the rate. Do you think this will really help?

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1652^#

發表於 12-5-25 18:18 |只看該作者

回覆 kakakaju 的帖子

Dear kakakaju,

It is understandable to get frustrated after all the time and effort invested into this treatment.

Although it is possible to transport your embryos from one lab to another, there is always administrative fees from both the sending and the receiving centres for the transport alone. If you don't "hate" your current doctor, I would suggest you can use up the 2 embryos first before considering your next move. If the 2 embryos are at blastocyst stage, given your age and number of previous attempts, you may opt to transfer both blastocysts in your next FET.

Indeed, age is the #1 factor that hinders pregnancy. Going back in time is something we cannot do. We can do assisted hatching, but it only helps when your embryo(s) are developmentally competent. Assisted hatching is a procedure that opens a hole, or thin a small area, on the shell of an embryo. It is believed that such hole, or thinned area, can provide an easy exit for the embryo to get out of its shell and then implant into the uterus. Usually, assisted hatching is done on day-3 embryos, so, you may need to know
1. if your embryos were frozen at day-3 or day-5;
2. if your lab is ok to carry out the procedure for your embryos.

cutecutetown

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1653^#

發表於 12-5-25 19:02 |只看該作者

回覆 cutecutetown 的帖子

Thanks very much cutecutetown for your information. I don't mind abotu the incurred cost but I think it's very troublesome after thinking about it all! I have booked three backup doctors. I don't "hate" my current doctor but I don't really feel too convincing he is not able to explain the reason apart from just "aged".

I will have to further investigate when they freeze my embyros and whether they can do assisted hatching. Moreover I will definitely request to transfer the two blastocysts as last time the doc and embyro specialist insisted they can ONLY put one...I must say that's one other factor which frustrates me so much.

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smt

別墅

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1654^#

發表於 12-5-29 15:38 |只看該作者

Hi cutecutetown,

Please excuse me that I did not go through all the postings here before asking you questions as someone may ask the same questions as mine.

I'm 42. I just had my OPU on last Sat however I was told that I cannot do the ET as my hormone level is a bit high

It's my 1st attempt. I have no idea how to ask questions. Therefore I'd only to follow what the dr told me to do. I am lucky to have you here to answer my questions. You have been so kind to us and don't mind to answer and explain to us again and again.

Today is Day3 after my egg retrieval. The lab informed me 4 embryos are going to be frozen today. (FYI, I have 6 eggs retrieved, 5 eggs were fertilized.) In what extend that the lab will consider to freeze Day3 embryos or Day5 blastocyst?

I know I will do the FET in my coming natural cycle however my period cycle is not regular. The dr gave me nasal spray which to control my hormone and the length of my cycle. My question is in a natural cycle, we will normally generate egg and has ovulation. What will the dr do to control this point? Do they need to do something to stop the egg generate or just leave it happen?

I admit that I do worry about the "survival" rate of the embryo after thawing

However, I know I have not much to do only to relax.....

smt

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1655^#

發表於 12-5-30 12:12 |只看該作者

回覆 smt 的帖子

Hello smt,

When your hormone (estradiol) is a bit high, this poses a possible risk for OHSS (ovarian hyperstimulation syndrome). In its mild form, you may simply feel bloated around your tummy; in a more severe form, your lungs may be filled with fluid, and in extreme cases, it could be life-threatening and admission into ICU is needed. When doing IVF, we cannot just look at the immediate OHSS risk, as it may also develop slowly; but when embryo(s) are transferred and implanted, pregnancy further elevates the risk. To do safe medicine, we have to put your health as the top priority. The hormone level will slowly come down to "normal" given some time, usually in about or less than a month things will return to its natural state.

For lab to decide Day3 vs Day5, it often depends on the lab's routine schedule. For example, in my lab, most patients do D3ET; so, most of the embryo freezing is done on day3. This is also to balance the fact the the longer you culture a batch of embryos, the more selection pressure you give them. Simply put, the longer you culture, the fewer embryos you have for freezing; just natural selection at work.

When we put everything through to day5, there is a higher chance of no viable embryo. My argument is that if an embryo is of no good, why bother keeping it to waste my patient's time? Of course my doctor's arguement is, what if it is the culture system that causes an embryo to stop growing? Since the doctors are still "gods" in many patients' eyes, it really depends on what the doctor's believes and also his/her passing of information to the patients in order to decide the best for the patients.

In your case, you are doing very well with 4 embryos frozen. Whether the doctor gives or not give medication in preparing an FET, the goal is to follow, or simulate, a cycle in which there is a follicular phase (the generation of a mature egg) and a luteal phase (the endometrium is receptive to an embryo). In order to transit from follicular to luteal phase, ovulation or anything that siimulate ovulation needs to happen.

It is true that an embryo may not survive the freeze-and-thaw process. For day3 embryos, depending on the freezing methodology, I have at least 80% survival (this is statisitics of over the past 10+ years). I have >90% survival with a "newer" method. I think you can stay optimistic at least for the coming FET.

Stay well,
cutecutetown

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smt

別墅

積分: 999

1656^#

發表於 12-5-30 14:18 |只看該作者

回覆 cutecutetown 的帖子

Hi cutecutetown,

Thank you for your reply.

Your detail explanation really reflief my worry and doubt. Indeed, I learnt a lot from this thread. I read up to page100 now

Somehow, I found most of information are quite interesting!

I am now suffering from bloating tummy and occasional pain on my ovaries. But, I am ok with this. I will overcome it.

I am looking forward to my coming FET. Hope those embryos are stronge enough until then.

Wish you doing well on your working position also your personal life!

smt

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cutecutetown Good, & thx! 發表於 12-5-30 21:02

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littletwinkle

子爵府

積分: 10045

畀面勳章環保接龍勳章

1657^#

發表於 12-5-30 14:28 |只看該作者

Hi cutecutetown,

想問一問, 是否胚胎雪的時侯已決定係day幾胚胎? 將來放雪胎唔可以改? 即是話雪day2將來就要放day2胚胎??

可唔可以到時解凍後再養多3日, 放day5囊胚呢? 一般lab是怎樣處理?

Thanks!

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1658^#

發表於 12-5-30 16:29 |只看該作者

Dear cutecutetown,

I just wanted to check why some doctor do not prefer to put in more than one blastocysts? Since my last one blastocyst failed, this time the doc is willing to put the remaining two inside me. I also recommended him to consider laser hatching, is laser hatching a better chance? I don't hate my doctor but if fate makes it difficult to have a successful IUI or IVF with him and this lab I must go.......

Thanks,
Kakakaju

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