when both groups of rats were offered a rich, creamy liquid high in sugar and fat, those patterns changed. All the animals ate without restraint. Levin said that when they are given such a palatable combination, “they will just gorge themselves.” Increasing only the fat content of a resistant rat’s diet won’t make the animal overeat or become obese. But feed it a high-fat, high-sugar diet, and it will grow just as fat as an obesity-prone rat on a high-calorie diet.