想生BB 今日: 6 | 主題: 109612

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1863^#

發表於 13-3-31 22:38 |只看該作者

回覆 villahome 的帖子

Hello villahome,
The oral and vaginal progesterone should not cause constipation. I think it may be anxiety causing constipation instead; maybe you are deliberately avoiding fruits and vegetables in these few days? Try to have them back in your meals and also do things that can help you reduce your stress and anxiety.

PCOS explained the suboptimal egg quality. Usually when a woman has too much a quantity, quality is compromised. Just my own experience that young women tend to get pregnant "easier" even when the embryo is of average quality. Do you have the other early blastocyst and the 2 morulae frozen for later use? The result (4 out of 20 eggs survived to day 5) is acceptable and reasonable. Do you know how many of the 20 eggs were fertilized, what is your hubby's sperm like? These also affect outcome as well.

cutecutetown

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villahome

複式洋房

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1864^#

發表於 13-3-31 23:26 |只看該作者

回覆：cutecutetown 的帖子

Thanks so much for your reply!

Re diet was worsened after ET, I think that affected the fibre intake. It has turned better since day 4, hope it will become normal soon.

Re fertilization rate, please refer to the breakdown as follows:

25/3 (day 0)
13 mature & sperms added, 5 not mature, 2 abnormal

26/3
11 fertilized, 2 abnormal

27/3
Grade 2 x 4, grade 2- x 6, 1 stopped growing

28/3
Grade 2 x 4, grade 2- x 5, grade 3 x 1

29/3
No report

30/3
Early x 2, morula x 2
Implanted 1 early, other freezed

Sperms reported ok except mobility just below standard.

Is this rate normal for PCOS patient at my age?

This is my first IVF. No worries, I\'m optimistic!

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marblecake88

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發表於 13-4-1 10:12 |只看該作者

引用：Dear+marblecake88, 因假期工作反而更忙，

原帖由 cutecutetown 於 13-03-31 發表
Dear marblecake88,
因假期工作反而更忙，遲了回覆，不好意思，你照了u/s如何?
有時對針藥反應因人而異，而 ...

Hello cutecutetown, 多謝你咁忙都抽空答我。今日再覆診，已打了十日針450Iu, 照到兩邊共有五粒, 有三粒已達18 x 20 , 兩粒14 x 15 左右，醫生叫我打多兩日藥，三日後才最卵，等多兩粒成熟D才抽。之前聽講18 mm已夠成熟，打多兩日才抽，以你經驗睇，其餘會否過熟？

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發表於 13-4-1 21:34 |只看該作者

回覆 villahome 的帖子

Dear villahome,
Now with the extra information, things are brighter!

You have 13 mature eggs with 11 of them fertilized; and out of the 11, you have 4 "usable" embryos. This is a very good result; usually, in couples with good prognosis, we expect ~1/3 of the fertilized eggs being "usable" by day-5. Hope I will hear good news from you soon.

cutecutetown

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發表於 13-4-1 21:44 |只看該作者

回覆：marblecake88 的帖子

Dear marblecake88,
三日後取卵，即打埋今日、明日450iu,應該ok的，不用擔心。
有時都視乎醫生習慣，通常卵泡到22mm都可以的。

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villahome

複式洋房

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1868^#

發表於 13-4-1 23:04 |只看該作者

回覆：cutecutetown 的帖子

Great to know!! Thanks :p

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1869^#

發表於 13-4-3 06:22 |只看該作者

回覆：cutecutetown 的帖子

Hey!

So I got back the fertilization and aneuploidy screening result. Details below:
1) retrieve 9 eggs, 8 fertilized
2) day 5: 3 early blast transferred. One is 5AA
3) day 6: one 4BB frozen

Pgd:
Only 2 are normal! One of them was transferred and the other one is frozen one.

Questions:
1) is 2 out of 8 a bad percentage?
2) that means 2 abnormal are already inside my body! If pregnant, may need to do something or the bad one usually just stop growing?
3) overall, is my number good or bad?

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1870^#

發表於 13-4-3 13:36 |只看該作者

回覆 jlin123 的帖子

Dear jlin123,
The pgd center you went to is a little strange in the sense that they would offer you pgd but transferred embryos before knowing the results. I would never want to do that. Besides, do you know how many chromosomes were tested for, i.e. a few or all 24 chromosomes? Will need to know this number first before attempting to answer your questions.

cutecutetown

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發表於 13-4-3 13:52 |只看該作者

回覆：cutecutetown 的帖子

Hi,

They check all 24 chromosomes. Also it\'s my own intent to transfer before knowing the results because I don\'t have a good history of frozen embryos. Usually they can\'t survive the thaw.

Hope this clarifies!

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1872^#

發表於 13-4-3 18:04 |只看該作者

回覆：jlin123 的帖子

Dear jlin123,
Ok, some centers have a quick turn around time for D5 or D6 ET so that you did not have to risk multiple pregnancies or yet another miscarriage. But now that what\'s done is done, let\'s hope for the best!

Back to your questions, 2 normals out of 8, not bad at all.
1. It may sound unreal, but I have seen cases with no normal embryo out of a total of >5.
2. Usually the abnormals will stop growing, but some will implant & cause early miscarriages; yet some can give live births (eg Down syndrome babies).
3. I hope your 5AA is the normal embryo! After getting pregnant from transferring a normal embryo, the chance to live birth is much higher, or the chance of a miscarriage is much lower.

Have you tried blastocyst freezing (ie Day5 freezing) before? I hardly have any blastocyst not surviving the thaw! Your 4BB will be fine, should you need it in the future.

Best wishes!!

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1873^#

發表於 13-4-4 10:01 |只看該作者

cutecutetown 發表於 13-4-3 18:04
Dear jlin123,
Ok, some centers have a quick turn around time for D5 or D6 ET so that you did not hav ...

Dear cutecutetown,

thanks for taking the time to answer my questions. yes i tried blastocyst freezing once as that's the only time out of 3 i actually have frozen one. And that one time failed.

I just got the hcg result back today (13dpo or 8dp5dt). It's 23! My doctor ask me to repeat the test in 2 days to see if it goes up. do you see any success cases that start with such a low hcg? i had 8 before which result in miscarriage. i hope this nightmare won't happen anymore. the only different sign this time is i have no bleeding or any discharge at all! no pain either. panty all clean. i don't think progesterone/estrace will delay my period as i always get some pink/red bleeding while on medications before pregnancy test.

any advise?? i really don't know what to do next if this one fails. would the IVF stimulation actually hurt the body if i do it over and over?

jlin

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發表於 13-4-4 13:31 |只看該作者

回覆 jlin123 的帖子

Dear jlin123,
You are definitely making good progress! An hcg value of 23 by the 8th day after embryo transfer is a good value; it is not low at all. However, you do need to repeat in 2 days and be cautiously optimistic.

Your previous hcg of 8 was from a D3 embryo, although the checking day/embryo developmental stage was similar to this cycle. I used to run hormonal tests and there is no absolute value you should achieve on certain day. What is critical now is to see if the value continues to go up; at this early stage, the value should about double every 2-3 days. Since you don't find any bleeding or discharge this time, I would treat it as a good sign!

My feeling is that you don't need another ivf cycle. Stay well :)
cutecutetown

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發表於 13-4-4 14:05 |只看該作者

引用：回覆+jlin123+的帖子 Dear+jlin123,You+ar

原帖由 cutecutetown 於 13-04-04 發表
回覆 jlin123 的帖子

Dear jlin123,

Thanks for your encouragement!! I\'ll just hope for the best!

So will ivf hurt the body if doing too much?

點評

cutecutetown Not that I have seen; no scientific publication on ivf harmful effects either. 發表於 13-4-5 00:42

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marblecake88

積分: 6252

1876^#

發表於 13-4-5 23:45 |只看該作者

引用：Dear+marblecake88, 三日後取卵，即打埋今

原帖由 cutecutetown 於 13-04-01 發表
Dear marblecake88,
三日後取卵，即打埋今日、明日450iu,應該ok的，不用擔心。
有時都視乎醫生習慣，通常卵 ...

Hello cutecutetown, 我好失望。今日抽卵，有六個卵泡，全抽了，但醫生說一粒卵子也沒有。今天再抽血，明天再call 我話我知驗血的hcg 水平。這種情況常見嗎？之前一個月食避孕藥會有影響嗎？還是退化問題？很惱人呀！

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發表於 13-4-6 08:24 |只看該作者

引用：回覆+jlin123+的帖子 Dear+jlin123,You+ar

原帖由 cutecutetown 於 13-04-04 發表
回覆 jlin123 的帖子

Dear jlin123,

Dear cutecutetown,

Got more update now. Need your input!

Summary:
4/3: hcg 23
4/4: some brown and pink discharge in morning! So I bed rest just to play safe. No more discharge since late afternoon.
4/5: panty totally clean for whole day! Hcg 61.

Dr ask to repeat test 4 days later. So is it low number still?? I hate it when it\'s so unclear still. Help!!

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發表於 13-4-6 11:32 |只看該作者

回覆：marblecake88 的帖子

Dear marblecake88,
I\'m very sorry to hear that. This happens occasionally, not a lot. Let\'s see what the blood test (hcg) say. Did you take your 破卵針at home?

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1879^#

發表於 13-4-6 11:38 |只看該作者

回覆：marblecake88 的帖子

之前一個月食避孕藥是不影響的，它只幫助卵子成長時更同步。卵巢功能可能差了一點點，因我記得你曾說今個周期開始時每邊卵巢只有各一個卵泡。

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