1. Unplug your wireless mouse, and use some old one (those with wire). See if it works or not. If work, then goto next step.
2. Backup your files immediately. Burn them to CD-ROM.
3. Reboot with Safe Mode first. Shutdown and reboot to normal mode. If not working, goto next step.
4. In normal mode, go to Control Panel and delete the 'display card driver' under 'System'. Reboot, windows should begin to search for your display card driver. Then try again.